Depression and anxiety symptoms post-stroke/TIA: prevalence and associations in cross-sectional data from a regional stroke registry.
Depression and anxiety symptoms post-stroke/TIA: prevalence and associations in cross-sectional data from a regional stroke registry.
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DOI：
10.1186/s12883-014-0198-8
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发表时间：
2014-10-01
期刊：
影响因子：
2.6
通讯作者：
Evans JJ
中科院分区：
文献类型：
--
作者：
Broomfield NM;Quinn TJ;Abdul-Rahim AH;Walters MR;Evans JJ
心境障碍常见于脑血管疾病患者。到目前为止，文献往往集中在抑郁症和中风患者身上，对短暂性脑缺血发作(TIA)患者的中风后焦虑或情绪障碍知之甚少。我们的目标是描述卒中和短暂性脑缺血发作队列中抑郁和焦虑症状的流行情况，并探索与临床和社会人口学因素的相关性。我们使用了全市范围的初级保健中风登记处(格拉斯哥中风当地增强服务)。所有社区居住的中风幸存者都包括在内。我们使用医院焦虑和抑郁量表(HADS)描述了抑郁和焦虑症状的横断面患病率。收集有关临床和人口学细节的数据，并进行单变量和多变量分析，以描述与HADS评分的关系。我们将那些被诊断为“中风”和“短暂性脑缺血发作”的患者作为单独的队列进行检查。从登记中可能符合条件的13,283名中风患者中，我们获得了4,079名HADS的完整数据。在3584名可能符合TIA标准的患者中，我们拥有1247名患者的完整HADS数据。在整个中风队列中，1181人(29%)的HADS焦虑评分提示可能或可能的焦虑；993人(24%)提示抑郁。短暂性脑缺血发作患者中，361例(29%)有焦虑，254例(21%)有抑郁。抑郁和焦虑症状的独立预测因素是女性、年龄较小和较高的社会经济剥夺得分(均p <； 0.001)。使用HADS，我们发现，在以社区为基础的脑血管疾病患者队列中，焦虑和抑郁症状的发生率很高。本文的在线版本(doi：10.1186/s12883-0140198-8)包含补充材料，授权用户可以使用。
Mood disorders are commonly seen in those with cerebrovascular disease. Literature to-date has tended to focus on depression and on patients with stroke, with relatively little known about post-stroke anxiety or mood disorder in those with transient ischaemic attack (TIA). We aimed to describe prevalence of depression and anxiety symptoms in stroke and TIA cohorts and to explore association with clinical and socio-demographic factors. We used a city wide primary care stroke registry (Glasgow Local Enhanced Service for Stroke - LES). All community dwelling stroke-survivors were included. We described cross-sectional prevalence of depression and anxiety symptoms using the Hospital Anxiety and Depression Scale (HADS). Data on clinical and demographic details was collected and univariable and multivariable analyses performed to describe associations with HADS scores. We examined those with a diagnosis of ‘stroke’ and ‘TIA’ as separate cohorts. From 13,283 potentially eligible stroke patients in the registry, we had full HADS data on 4,079. Of the 3,584 potentially eligible TIA patients, we had full HADS data on 1,247 patients. Across the stroke cohort, 1181 (29%) had HADS anxiety scores suggestive of probable or possible anxiety; 993 (24%) for depression. For TIA patients, 361 (29%) had anxiety and 254 (21%) had depression. Independent predictors of both depression and anxiety symptoms were female sex, younger age and higher socioeconomic deprivation score (all p < 0.001). Using HADS, we found a high prevalence of anxiety and depression symptoms in a community-based cohort of patients with cerebrovascular disease. The online version of this article (doi:10.1186/s12883-014-0198-8) contains supplementary material, which is available to authorized users.
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影响因子：
120.7
作者：
GLASSMAN, AH;HELZER, JE;JOHNSON, J
通讯作者：
JOHNSON, J
影响因子：
2.9
作者：
Lees, Rosalind;Stott, David J.;Broomfield, Niall M.
通讯作者：
Broomfield, Niall M.
DOI：
10.1097/hjr.0b013e3280142a02
发表时间：
2007-08-01
影响因子：
--
作者：
Rothenbacher, Dietrich;Hahmann, Harry;Brenner, Hermann
通讯作者：
Brenner, Hermann
影响因子：
--
作者：
Kessler, RC;Berglund, P;Walters, EE
通讯作者：
Walters, EE
影响因子：
8.3
作者：
Turner, Alyna;Hambridge, John;Hackett, Maree
通讯作者：
Hackett, Maree