Antimicrobial Resistance Monitoring of Water Environments: A Framework for Standardized Methods and Quality Control.
Antimicrobial Resistance Monitoring of Water Environments: A Framework for Standardized Methods and Quality Control.
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DOI：
10.1021/acs.est.1c08918
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发表时间：
2022-07-05
影响因子：
11.4
通讯作者：
Pruden, Amy
中科院分区：
文献类型：
--
作者：
Liguori, Krista;Keenum, Ishi;Davis, Benjamin C.;Calarco, Jeanette;Milligan, Erin;Harwood, Valerie J.;Pruden, Amy
抗菌素耐药性（AMR）是一个巨大的社会挑战，在水环境中具有重要的维度，有助于其演变和传播。环境监测可以为减缓抗生素耐药性的传播提供重要信息;这包括评估在人群中传播的抗生素耐药性基因（ARG），确定耐药性演变和传播的关键热点，为流行病学和人类健康风险评估模型提供信息，以及量化生活污水基础设施的去除效率。然而，监测水环境中AMR的标准化方法对于产生解决这些问题所需的可比数据集至关重要。在这里，我们试图建立这样的标准化框架的科学共识，通过文献综述，调查和研讨会，利用学术，政府，咨询和水公用事业专业人士的专业知识，评估废水，再生水和地表水AMR监测的科学和实践状况。标准化方法是建立国际可比数据库以监测水环境抗生素耐药性的关键下一步。
Antimicrobial resistance (AMR) is a grand societal challenge with important dimensions in the water environment that contribute to its evolution and spread. Environmental monitoring could provide vital information for mitigating the spread of AMR; this includes assessing antibiotic resistance genes (ARGs) circulating among human populations, identifying key hotspots for evolution and dissemination of resistance, informing epidemiological and human health risk assessment models, and quantifying removal efficiencies by domestic wastewater infrastructure. However, standardized methods for monitoring AMR in the water environment will be vital to producing the comparable data sets needed to address such questions. Here we sought to establish scientific consensus on a framework for such standardization, evaluating the state of the science and practice of AMR monitoring of wastewater, recycled water, and surface water, through a literature review, survey, and workshop leveraging the expertise of academic, governmental, consulting, and water utility professionals. Standardized methods are a crucial next step in creating internationally comparable databases for antibiotic resistance monitoring of water environments.
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影响因子：
11.4
作者：
Flach, Carl-Fredrik;Genheden, Maja;Larsson, D. G. Joakim
通讯作者：
Larsson, D. G. Joakim
DOI：
10.1093/jac/dkaa345
发表时间：
2020-12-01
期刊：
The Journal of antimicrobial chemotherapy
影响因子：
--
作者：
Bortolaia V;Kaas RS;Ruppe E;Roberts MC;Schwarz S;Cattoir V;Philippon A;Allesoe RL;Rebelo AR;Florensa AF;Fagelhauer L;Chakraborty T;Neumann B;Werner G;Bender JK;Stingl K;Nguyen M;Coppens J;Xavier BB;Malhotra-Kumar S;Westh H;Pinholt M;Anjum MF;Duggett NA;Kempf I;Nykäsenoja S;Olkkola S;Wieczorek K;Amaro A;Clemente L;Mossong J;Losch S;Ragimbeau C;Lund O;Aarestrup FM
通讯作者：
Aarestrup FM
具有内部标准标准的基因的宏基因组量化。
影响因子：
6.4
作者：
Crossette E;Gumm J;Langenfeld K;Raskin L;Duhaime M;Wigginton K
通讯作者：
Wigginton K
影响因子：
56.3
作者：
Cabello, Felipe C.;Godfrey, Henry P.;Dolz, Humberto J.
通讯作者：
Dolz, Humberto J.
影响因子：
14.9
作者：
Doster, Enrique;Lakin, Steven M.;Morley, Paul S.
通讯作者：
Morley, Paul S.