HIV-1-Mediated Acceleration of Oncovirus-Related Non-AIDS-Defining Cancers.
HIV-1-Mediated Acceleration of Oncovirus-Related Non-AIDS-Defining Cancers.
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DOI:
10.3390/biomedicines10040768
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发表时间:
2022-03-25
期刊:
影响因子:
4.7
通讯作者:
Borgmann, Kathleen
中科院分区:
文献类型:
--
作者:
Proulx, Jessica;Ghaly, Maria;Park, In-Woo;Borgmann, Kathleen
With the advent of combination antiretroviral therapy (cART), overall survival has been improved, and the incidence of acquired immunodeficiency syndrome (AIDS)-defining cancers has also been remarkably reduced. However, non-AIDS-defining cancers among human immunodeficiency virus-1 (HIV-1)-associated malignancies have increased significantly so that cancer is the leading cause of death in people living with HIV in certain highly developed countries, such as France. However, it is currently unknown how HIV-1 infection raises oncogenic virus-mediated cancer risks in the HIV-1 and oncogenic virus co-infected patients, and thus elucidation of the molecular mechanisms for how HIV-1 expedites the oncogenic viruses-triggered tumorigenesis in the co-infected hosts is imperative for developing therapeutics to cure or impede the carcinogenesis. Hence, this review is focused on HIV-1 and oncogenic virus co-infection-mediated molecular processes in the acceleration of non-AIDS-defining cancers.
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影响因子:
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作者:
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通讯作者:
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DOI:
10.1016/j.bbrc.2020.05.188
发表时间:
2020-09-03
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期刊:
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影响因子:
--
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通讯作者:
Rizk N
影响因子:
29.4
作者:
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通讯作者:
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