Body builder: from synthetic cells to engineered tissues.

Body builder: from synthetic cells to engineered tissues.
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DOI:
10.1016/j.ceb.2018.04.010
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发表时间:
2018-10
影响因子:
7.5
通讯作者:
Cheng K
Cheng K
中科院分区:
生物学2区
文献类型:
--
作者:
Hu S;Ogle BM;Cheng K

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It’s estimated that 18 Americans die every day waiting for an organ donation. And even if a patient receives the organ that s/he needs, there is still >10% chance that the new organ will not work. The field of tissue engineering and regenerative medicine aims to actively use a patient’s own cells, plus biomaterials and factors, to grow an organ or to restore normal functions of that organ, which would eliminate the need for donors and the risk of organ rejection. In this review, we summarized recent advances in fabricating synthetic cells and engineering tissue, with a specific focus on cardiac regenerative medicine and tissue engineering. At the end, we pointed to challenges and future directions for the field.
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