Seroprevalence and risk factors of human cytomegalovirus infection in the eastern Chinese population
Seroprevalence and risk factors of human cytomegalovirus infection in the eastern Chinese population
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中国东部人群人类巨细胞病毒感染的血清阳性率及危险因素
DOI：
10.1007/s00705-009-0339-3
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发表时间：
2009-03
影响因子：
2.7
通讯作者：
Zhang Xiaomei
中科院分区：
文献类型：
--
作者：
Wang Shukang;Zhou Yabin;Zhao Ping;Ji Chunyan;Yu Xiuping;Xue Fuzhong;Ma Daoxin;Zhang Xiaomei
众所周知，人类巨细胞病毒 (HCMV) 感染的流行病学和临床结果因国家/地区而异，并且与社会经济背景相关。迄今为止，来自发展中国家的数据很少，这些国家的传染病总体负担往往较高。因此，我们分析了从中国东部地区随机抽取的3,740人的血清阳性率，旨在确定HCMV感染的血清阳性率和危险因素。总体血清阳性率为48.07%，经济社会发达的内陆地区高于沿海发达地区。女性血清阳性率（54.60%）显着高于男性（41.58%）（P<0.001）。从职业来看，农民（61.54%）和医生（68.48%）的血清阳性率高于其他职业（P<0.0001）。血清流行率与年龄增加之间存在显着相关性（P < 0.05）。我们的研究可能有助于确定未来 HCMV 疫苗接种的重点人群。
Epidemiology and clinical outcomes of human cytomegalovirus (HCMV) infection are known to vary between countries and are associated with socio-economic background. So far, few data are available from developing countries, where the overall burden of infectious diseases is frequently higher. Therefore, we analyzed the seroprevalence in a population of 3,740 individuals selected randomly from eastern China, aiming to determine the seroprevalence of and risk factors for HCMV infection. The overall seroprevalence was 48.07%, higher in the socioeconomically developing inland districts than in the developed forelands. The seroprevalence in females (54.60%) was significantly higher than that in males (41.58%) (P< 0.001). As for profession, peasants (61.54%) and doctors (68.48%) had a higher seropositive rate than members of other professions (P< 0.0001). A significant association between seroprevalence and increasing age was identified (P< 0.05). Our study might help to identify appropriate populations on which to focus for future HCMV vaccination.
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影响因子：
1.3
作者：
Boeckh, M;Fries, B;Nichols, WG
通讯作者：
Nichols, WG
影响因子：
2.9
作者：
J. Shenai
通讯作者：
J. Shenai
DOI：
--
发表时间：
2001-02
期刊：
Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University
影响因子：
--
作者：
G. Wu;S. Chen;L. Y. Chen
通讯作者：
G. Wu;S. Chen;L. Y. Chen
DOI：
10.1097/00006454-198401000-00024
发表时间：
1983-06
期刊：
--
影响因子：
--
作者：
J. Remington;J. Klein
通讯作者：
J. Remington;J. Klein
DOI：
--
发表时间：
2002
期刊：
--
影响因子：
--
作者：
Zhao Zhe
通讯作者：
Zhao Zhe