Effects of Four Different Dietary Fibre Supplements on Weight Loss and Lipid and Glucose Serum Profiles during Energy Restriction in Patients with Traits of Metabolic Syndrome: A Comparative, Randomized, Placebo-Controlled Study.
Effects of Four Different Dietary Fibre Supplements on Weight Loss and Lipid and Glucose Serum Profiles during Energy Restriction in Patients with Traits of Metabolic Syndrome: A Comparative, Randomized, Placebo-Controlled Study.
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DOI：
10.3390/foods12112122
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发表时间：
2023-05-24
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影响因子：
--
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肥胖及其相关并发症需要各种生活方式的改变和治疗选择。膳食补充剂被认为是传统疗法的一个有吸引力的替代品，主要是因为它们对普通人群来说是容易获得的。本研究的目的是调查能量限制（ER）和四种膳食补充剂的组合对100名超重或肥胖参与者的人体测量学和生化参数变化的累加效应，这些参与者被随机分配一种含有不同膳食纤维的膳食纤维补充剂或安慰剂，为期8周。结果证实，在研究开始后的第4周和第8周，纤维补充剂加ER显著（p < 0.01）降低了体重、体重指数（BMI）、脂肪量和内脏脂肪，改善了脂质谱和炎症，而安慰剂组在一些参数上仅在ER服用8周后才观察到显著差异。含有葡甘露聚糖、菊粉、车前草和苹果纤维的纤维补充剂在降低BMI、体重和CRP方面最有效（与干预结束时的安慰剂相比，BMI和体重的p = 0.018， CRP的p = 0.034）。总的来说，结果表明膳食纤维补充剂与内质网结合可能对减肥和代谢有额外的影响。因此，服用膳食纤维补充剂可能是改善肥胖和超重个体体重和代谢健康的可行方法。
Obesity and its associated complications require various lifestyle changes and treatment options. Dietary supplements are considered an attractive alternative to traditional therapy, mainly because they are accessible to the general population. The aim of this study was to investigate the additive effects of a combination of energy restriction (ER) and four dietary supplements on changes in the anthropometric and biochemical parameters in 100 overweight or obese participants who were randomly assigned one of the dietary fibre supplements containing different dietary fibres or a placebo for 8 weeks. The results confirmed that fibre supplements plus ER significantly (p < 0.01) reduced the body weight, body mass index (BMI), fat mass, and visceral fat and ameliorated the lipid profile and inflammation at 4 and 8 weeks after the start of the study, while in the placebo group, significant differences in some parameters were observed only after 8 weeks of ER. A fibre supplement containing glucomannan, inulin, psyllium, and apple fibre was the most effective at reducing the BMI, body weight, and CRP (p = 0.018 for BMI and body weight and p = 0.034 for CRP compared to placebo at the end of the intervention). Overall, the results suggest that dietary fibre supplements in combination with ER may have additional effects on weight loss and the metabolic profile. Therefore, taking dietary fibre supplements may be a feasible approach to improve weight and metabolic health in obese and overweight individuals.
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影响因子：
5
作者：
Hess, Anne Lundby;Benitez-Paez, Alfonso;Larsen, Thomas Meinert
通讯作者：
Larsen, Thomas Meinert
影响因子：
5.4
作者：
HOLT, S;BRAND, J;HANSKY, J
通讯作者：
HANSKY, J
影响因子：
4.2
作者：
Brighenti, Furio
通讯作者：
Brighenti, Furio
影响因子：
5.8
作者：
Corella, D;Qi, L;Ordovas, JM
通讯作者：
Ordovas, JM
影响因子：
2.2
作者：
El Khoury D;Cuda C;Luhovyy BL;Anderson GH
通讯作者：
Anderson GH