Epidemiology of psoriasis and palmoplantar pustulosis: a nationwide study using the Japanese national claims database.
Epidemiology of psoriasis and palmoplantar pustulosis: a nationwide study using the Japanese national claims database.
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DOI：
10.1136/bmjopen-2014-006450
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发表时间：
2015-01-14
期刊：
影响因子：
2.9
通讯作者：
Nakagawa H
中科院分区：
文献类型：
--
作者：
Kubota K;Kamijima Y;Sato T;Ooba N;Koide D;Iizuka H;Nakagawa H
主要目的是估计日本牛皮癣和棕榈脓疱病（PPP）的全国患病率。 Mellitus，高脂血症和高血压。
在2010年4月至2011年3月之间，使用日本国家数据库确定了牛皮癣或PPP诊断代码的患者。
565 903例牛皮癣或PPP患者被排除在外。
我们使用普查数据计算了国家患病率。这些措施是针对牛皮癣和PPP的两种广泛疾病类别的分别估算的，但在所有患者中均不估计，因为两种疾病类别的差异很大。
牛皮癣和PPP的全国患病率分别为0.34％（95％CI 0.34％至0.34％）和0.12％（0.12％至0.12％）。牛皮癣的寒冷季节为-0.3％（-0.5％至-0.1％），PPP的寒冷季节为10.0％（9.8％至10.3％）。 3.4％），3.2％（2.8％至3.6％）和5.1％（4.7％至5.6％）的糖尿病，高脂血症和高血压分别在PPP中观察到合并症的患病率无显着差异。
在这项描述性研究中估计的日本牛皮癣和PPP患者的疾病活动的季节性差异和合并症的患病率可能被用作未来研究的基本信息。
The primary objective was to estimate the national prevalence of psoriasis and palmoplantar pustulosis (PPP) in Japan. Secondary objectives were to determine (1) whether psoriasis and PPP disease activity varies by season, and (2) whether disease severity is associated with concurrent diabetes mellitus, hyperlipidaemia and hypertension. Patients with a psoriasis or PPP diagnosis code between April 2010 and March 2011 were identified using a Japanese national database. 565 903 patients with psoriasis or PPP were identified. No patient was excluded. National prevalence was calculated using census data. We estimated the difference in the proportion of patients who used healthcare services, as a proxy for disease activity, between the hot and cold seasons and the difference in the standardised prevalence of comorbidities between severe and mild disease. The measures were estimated separately for the two broad disease categories of psoriasis and PPP but not in all patients as planned because the two disease categories had major differences. The national prevalence of psoriasis and PPP was 0.34% (95% CI 0.34% to 0.34%) and 0.12% (0.12% to 0.12%), respectively. The difference in the proportion of patients who used healthcare services in the hot compared to the cold season was −0.3% (−0.5% to −0.1%) for psoriasis and 10.0% (9.8% to 10.3%) for PPP. The difference in the standardised prevalence between severe and mild psoriasis was 3.1% (2.7% to 3.4%), 3.2% (2.8% to 3.6%) and 5.1% (4.7% to 5.6%) for concurrent diabetes mellitus, hyperlipidaemia and hypertension, respectively. No significant difference in the prevalence of comorbidity was observed for PPP. The national prevalence, seasonal variation in disease activity and prevalence of comorbidities in Japanese patients with psoriasis and PPP estimated in this descriptive study may be used as basic information for future studies.
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影响因子：
120.7
作者：
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通讯作者：
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