Surveillance for enterovirus D68 in colorado children reveals continued circulation.

Surveillance for enterovirus D68 in colorado children reveals continued circulation.
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DOI:
10.1016/j.jcv.2017.05.009
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发表时间:
2017-07
期刊:
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology
影响因子:
--
通讯作者:
Dominguez SR
Dominguez SR
中科院分区:
其他
文献类型:
--
作者:
Messacar K;Robinson CC;Pretty K;Yuan J;Dominguez SR

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2014年8月至12月,美国爆发了规模最大、传播最广的肠道病毒D68呼吸道疾病疫情,49个州有1153人确诊感染。2014年爆发后的肠道病毒D68的流行病学尚不清楚。这项研究旨在描述2014-2016年间科罗拉多州儿童中肠道病毒D68传播的流行病学。这是一项对2014年7月至10月至2016年7月至10月在科罗拉多儿童医院(CHCO)进行的肠道病毒D68感染的前瞻性观察监测研究,该医院是科罗拉多州奥罗拉市的一家第四级保健儿童医院。在重症监护病房病人鼻病毒/肠病毒阳性的呼吸道样本中,2014年314份样本中有98份(31.2%)、2015年的307份样本中没有一份(0%)、2016年的240份样本中有19份(7.9%)被确认为肠道病毒D68。在前瞻性主动监测期内所有患者的呼吸道样本中,2015年的1469份(0%)和1403份中的46份(3.3%)肠道病毒D68均未呈阳性。对一家第四级护理儿童医院的呼吸道样本进行的肠道病毒D68监测显示,2014年夏末至2016年初秋期间,肠道病毒D68的传播呈现季节性规律。对呼吸道样本的持续监测对于确定循环模式和了解这种新出现病原体的流行病学是必要的。
The largest, most widespread outbreak of enterovirus D68 respiratory disease occurred from August to December of 2014 in the United States with 1,153 confirmed infections in 49 states. The epidemiology of enterovirus D68 following the 2014 outbreak is unknown. This study seeks to describe the epidemiology of enterovirus D68 circulation amongst Colorado children from 2014–2016. This is a prospective observational surveillance study of enterovirus D68 infection amongst children tested for respiratory pathogens from July–October 2014–2016 at Children’s Hospital Colorado (CHCO), a quaternary care children’s hospital in Aurora, CO. Amongst rhinovirus/enterovirus positive respiratory specimens from intensive care unit patients, ninety-eight of 314 (31.2%) in 2014, none of 307 (0%) specimens in 2015, and 19 of 240 (7.9%) specimens in 2016 were identified as enterovirus D68. Amongst respiratory specimens from all patients during the prospective active surveillance period, none of 1469 (0%) in 2015 and 46 of 1403 (3.3%) were positive for enterovirus D68. Surveillance for enterovirus D68 amongst respiratory specimens at a quaternary care children’s hospital revealed a seasonal pattern of circulation in the late summer to early fall of 2014 and 2016. Continued surveillance of respiratory specimens is necessary to define the circulation pattern and understand the epidemiology of this emerging pathogen.
急性弛缓性脊髓炎儿童肠道病毒 D68 感染,美国科罗拉多州,2014 年。
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