An aberrant precision account of autism.

An aberrant precision account of autism.
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DOI:
10.3389/fnhum.2014.00302
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发表时间:
2014
影响因子:
2.9
通讯作者:
Friston KJ
Friston KJ
中科院分区:
医学3区
文献类型:
--
作者:
Lawson RP;Rees G;Friston KJ

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自闭症是一种神经发育障碍,其特征是社交障碍,兴趣受限和重复行为。最近一篇发人深省的文章提出了一个规范的解释,自闭症的知觉症状的贝叶斯推理失败(佩利卡诺和伯尔,)。作为回应,我们提出,当贝叶斯推理基于其神经实例时-即预测编码-自闭症感知的许多特征可以归因于大脑中分层信息传递背景下的异常精确度(或关于精确度的信念)(Friston et al.,)。在这里,我们解开自闭症异常精确的帐户。具体来说,我们认为经验的发现,直接或间接地发言的神经生物学机制是一致的异常编码的精度在自闭症,特别是,不平衡的精度归因于感官证据相对于先前的信念。
Autism is a neurodevelopmental disorder characterized by problems with social-communication, restricted interests and repetitive behavior. A recent and thought-provoking article presented a normative explanation for the perceptual symptoms of autism in terms of a failure of Bayesian inference (Pellicano and Burr,). In response, we suggested that when Bayesian inference is grounded in its neural instantiation—namely, predictive coding—many features of autistic perception can be attributed to aberrant precision (or beliefs about precision) within the context of hierarchical message passing in the brain (Friston et al.,). Here, we unpack the aberrant precision account of autism. Specifically, we consider how empirical findings—that speak directly or indirectly to neurobiological mechanisms—are consistent with the aberrant encoding of precision in autism; in particular, an imbalance of the precision ascribed to sensory evidence relative to prior beliefs.
DOI: 10.1016/j.neuron.2012.10.038
发表时间: 2012-11-21
期刊: Neuron
影响因子: 16.2
作者:
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