Chronic pain and obesity in elderly people: results from the Einstein aging study.

Chronic pain and obesity in elderly people: results from the Einstein aging study.
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DOI:
10.1111/j.1532-5415.2008.02089.x
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发表时间:
2009-01
影响因子:
6.3
通讯作者:
Lipton RB
Lipton RB
中科院分区:
医学1区
文献类型:
--
作者:
McCarthy LH;Bigal ME;Katz M;Derby C;Lipton RB

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确定老年人慢性疼痛的患病率及其与肥胖、相关合并症和危险因素的关系。以社区为基础的横断面研究840名70岁或以上老年受试者的代表性社区样本。我们检查了慢性疼痛的患病率及其与肥胖(由体重指数定义的类别),其他医学风险因素和精神病合并症的关系。慢性疼痛定义为在过去3个月的部分、大部分或全部时间内至少中度疼痛(10分量表中≥ 4)。样本大多为女性(62.8%),平均年龄为80岁(范围70-101岁)。慢性疼痛的患病率为52%(男性39.7%;女性58.9%)。慢性疼痛患者更可能报告抑郁症(OR 2.5,95%CI=1.40-4.55)和焦虑症(OR 2.3,95%CI=1.22-4.64)。与正常体重个体(BMI 18.5-24.9)相比,肥胖受试者(BMI 30-34.9)发生慢性疼痛的可能性是正常体重个体的两倍(OR 2.1,95%CI=1.33-3.28),而重度肥胖受试者(BMI ≥ 35)发生慢性疼痛的可能性是正常体重个体的四倍多(OR 4.5,95%CI=1.85-12.63)。与非肥胖受试者相比,肥胖受试者更有可能出现头部、颈部/肩部、背部、腿部/脚部和腹部/骨盆慢性疼痛。在多变量模型中,在校正年龄、性别、糖尿病、高血压、抑郁、焦虑和教育后,肥胖(OR 2.0,95%CI = 1.27-3.26)和重度肥胖(OR 4.1,95%CI=1.57-10.82)与慢性疼痛相关。慢性疼痛在老年人群中很常见,对女性的影响大于男性,并且与肥胖高度相关。
To determine the prevalence of chronic pain in the elderly and its relationship with obesity, associated co-morbidities and risk factors. Cross-Sectional Community-based A representative community sample of 840 elderly subjects age 70 or older. We examined the prevalence of chronic pain and its relationship with obesity (categories defined by body mass index), other medical risk factors and psychiatric comorbidities. Chronic pain was defined by pain of at least moderate severity (≥ 4 on a 10-point scale) some, most or all of the time for the past three months. The sample was mostly female (62.8%) and the average age was 80 years (range 70–101 years). The prevalence of chronic pain was 52% (39.7% in men; 58.9% in women). Those with chronic pain were more likely to report a diagnosis of depression (OR 2.5, 95%CI=1.40–4.55) and anxiety (OR 2.3, 95%CI=1.22–4.64). Compared to individuals with normal weight (BMI 18.5–24.9), obese subjects (BMI 30–34.9) were twice as likely (OR 2.1, 95%CI=1.33–3.28) while severely obese subjects (BMI ≥ 35) were more than four times as likely (OR 4.5, 95%CI=1.85–12.63) to have chronic pain. Obese subjects were significantly more likely to have chronic pain in the head, neck/shoulder, back, legs/feet, and abdomen/pelvis than non-obese subjects. In multivariate models, obesity (OR 2.0, 95%CI=1.27–3.26) and severe obesity (OR 4.1, 95%CI=1.57–10.82) were associated with chronic pain after adjusting for age, sex, diabetes, hypertension, depression, anxiety and education. Chronic pain is common in this elderly population, affects women more than men and is highly associated with obesity.
DOI: 10.1212/01.wnl.0000197218.05284.82
发表时间: 2006-02-28
期刊: NEUROLOGY
影响因子: 9.9
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发表时间: 2006-03-01
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DOI: 10.1016/j.ejpain.2004.02.002
发表时间: 2004-12-01
影响因子: 3.6
作者:
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DOI: 10.1016/s0304-3959(01)00452-3
发表时间: 2002-04-01
期刊: PAIN
影响因子: 7.4
作者:
McBeth, J;Macfarlane, GJ;Silman, AJ
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DOI: 10.1016/s0168-8227(98)00109-0
发表时间: 1998-12-01
影响因子: 5.1
作者:
Winkler, G;Salamon, F;Cseh, K
通讯作者: Cseh, K