The role of sleep in forming a memory representation of a two-dimensional space.
The role of sleep in forming a memory representation of a two-dimensional space.
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DOI：
10.1002/hipo.22157
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发表时间：
2013-12
期刊：
影响因子：
3.5
通讯作者：
Thompson-Schill, Sharon L.
中科院分区：
文献类型：
--
作者：
Coutanche, Marc N.;Gianessi, Carol A.;Chanales, Avi J. H.;Willison, Kate W.;Thompson-Schill, Sharon L.
来自人类和动物模型的大量证据表明，睡眠有助于巩固新学到的信息。睡眠在将信息整合到相互关联的记忆表征中的确切作用还不太清楚。基于先前的研究结果，即睡眠后（与清醒相比），人们能够更好地在简单的层次结构中进行学习关联的推断，我们询问睡眠如何帮助巩固更复杂的表征空间中的关系。我们教60名受试者成对建筑物之间的空间关系，这些建筑物（参与者不知道）形成了一个二维网格。重要的是，参与者只被教导了许多可能的空间关系的一个子集，这使他们能够潜在地推断出其余的空间关系。在12小时的时间内，包括或不包括正常的睡眠时间，参与者返回实验室。我们检查了每个参与者的二维空间地图的质量，以及他们对建筑物之间相对距离的了解。经过12小时的睡眠，受试者可以更准确地映射整个空间比受试者谁只经历了清醒。结合未教，但推断，协会特别改善。我们进一步发现，参与者的距离判断表现与自我报告的导航风格有关，但仅在睡眠后。这些发现表明，经过一夜睡眠的巩固开始将关系整合到相互关联的复杂表征中，以支持空间关系推理的方式。
There is ample evidence from human and animal models that sleep contributes to the consolidation of newly learned information. The precise role of sleep for integrating information into interconnected memory representations is less well understood. Building on prior findings that following sleep (as compared to wakefulness) people are better able to draw inferences across learned associations in a simple hierarchy, we ask how sleep helps consolidate relationships in a more complex representational space. We taught 60 subjects spatial relationships between pairs of buildings, which (unknown to participants) formed a two-dimensional grid. Critically, participants were only taught a subset of the many possible spatial relations, which allowed them to potentially infer the remainder. After a 12 h period that either did or did not include a normal period of sleep, participants returned to the lab. We examined the quality of each participant's map of the two-dimensional space, and their knowledge of relative distances between buildings. After 12 h with sleep, subjects could more accurately map the full space than subjects who experienced only wakefulness. The incorporation of untaught, but inferable, associations was particularly improved. We further found that participants' distance judgment performance related to self-reported navigational style, but only after sleep. These findings demonstrate that consolidation over a night of sleep begins to integrate relations into an interconnected complex representation, in a way that supports spatial relational inference.
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DOI：
10.1073/pnas.94.13.7109
发表时间：
1997-06-24
影响因子：
11.1
作者：
Dusek, JA;Eichenbaum, H
通讯作者：
Eichenbaum, H
影响因子：
3
作者：
Hegarty, M;Richardson, AE;Subbiah, I
通讯作者：
Subbiah, I
影响因子：
2
作者：
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通讯作者：
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影响因子：
11.3
作者：
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通讯作者：
KUPFER, DJ
影响因子：
9.2
作者：
Ellenbogen, Jeffrey M.;Hulbert, Justin C.;Thompson-Schill, Sharon L.
通讯作者：
Thompson-Schill, Sharon L.