The role of the right inferior frontal gyrus: inhibition and attentional control.

The role of the right inferior frontal gyrus: inhibition and attentional control.
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DOI:
10.1016/j.neuroimage.2009.12.109
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发表时间:
2010-04-15
期刊:
影响因子:
5.7
通讯作者:
Owen AM
Owen AM
中科院分区:
医学1区
文献类型:
--
作者:
Hampshire A;Chamberlain SR;Monti MM;Duncan J;Owen AM

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关于右额下回(RIFG)在一种特殊形式的执行控制(称为反应抑制)中的作用越来越受到关注。然而,用于检查反应抑制点的神经活动的任务很少控制注意力需求的潜在混杂效应。特别是,目前还不清楚是否RIFG是专门参与抑制控制,或参与更普遍的检测突出或任务相关的线索。目前的fMRI研究试图澄清的RIFG在执行控制中的作用,通过保持最流行的反应抑制任务之一的停止信号任务的刺激条件不变,而不同的反应,所需的接收停止信号提示。我们的研究结果表明,RIFG被招募时,重要的线索被检测到,无论该检测是其次是运动反应的抑制,运动反应的产生,或根本没有外部反应。
There is growing interest regarding the role of the right inferior frontal gyrus (RIFG) during a particular form of executive control referred to as response inhibition. However, tasks used to examine neural activity at the point of response inhibition have rarely controlled for the potentially confounding effects of attentional demand. In particular, it is unclear whether the RIFG is specifically involved in inhibitory control, or is involved more generally in the detection of salient or task relevant cues. The current fMRI study sought to clarify the role of the RIFG in executive control by holding the stimulus conditions of one of the most popular response inhibition tasks–the Stop Signal Task–constant, whilst varying the response that was required on reception of the stop signal cue. Our results reveal that the RIFG is recruited when important cues are detected, regardless of whether that detection is followed by the inhibition of a motor response, the generation of a motor response, or no external response at all.
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