Anthrax lethal and edema toxins in anthrax pathogenesis.
Anthrax lethal and edema toxins in anthrax pathogenesis.
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DOI:
10.1016/j.tim.2014.02.012
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发表时间:
2014-06
影响因子:
15.9
通讯作者:
Leppla, Stephen H.
中科院分区:
文献类型:
--
作者:
Liu, Shihui;Moayeri, Mahtab;Leppla, Stephen H.
The pathophysiological effects resulting from many bacterial diseases are caused by exotoxins released by the bacteria. Bacillus anthracis, a spore-forming bacterium, is such a pathogen, causing anthrax through a combination of bacterial infection and toxemia. B. anthracis causes natural infection in humans and animals and has been a top bioterrorism concern since the 2001 anthrax attacks in the USA. The exotoxins secreted by B. anthracis use CMG2 as the major toxin receptor and play essential roles in pathogenesis during the entire course of the disease. This review focuses on the activities of anthrax toxins and their roles in initial and late stages of anthrax infection.
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影响因子:
5.3
作者:
Coggeshall KM;Lupu F;Ballard J;Metcalf JP;James JA;Farris D;Kurosawa S
通讯作者:
Kurosawa S
影响因子:
6.4
作者:
Corre, Jean-Philippe;Piris-Gimenez, Alejandro;Goossens, Pierre L.
通讯作者:
Goossens, Pierre L.
影响因子:
4.2
作者:
Chen Z;Moayeri M;Purcell R
通讯作者:
Purcell R
DOI:
10.1083/jcb.200211018
发表时间:
2003-02-03
期刊:
The Journal of cell biology
影响因子:
--
作者:
Abrami L;Liu S;Cosson P;Leppla SH;van der Goot FG
通讯作者:
van der Goot FG
影响因子:
2.8
作者:
Dal Molin, Federica;Fasanella, Antonio;Tonello, Fiorella
通讯作者:
Tonello, Fiorella