Herpesviruses: latency and reactivation - viral strategies and host response.
Herpesviruses: latency and reactivation - viral strategies and host response.
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DOI:
10.3402/jom.v5i0.22766
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发表时间:
2013-10-25
影响因子:
4.5
通讯作者:
Grinde B
中科院分区:
文献类型:
--
作者:
Grinde B
Eight members of the Herpesviridae family commonly infect humans, and close to 100% of the adult population is infected with at least one of these. The five that cause the most health concerns are: herpes simplex virus (HSV) type 1 and 2, Epstein–Barr virus (EBV), cytomegalovirus (CMV), and varicella zoster virus (VZV). In addition, there are human herpes virus (HHV) types 6–8. The review starts by introducing possible viral strategies in general. The particular biology and host relationship of the various human herpesviruses, including their pathology, are examined subsequently. Factors that contribute to the maintenance of latency and reactivation of viral replication are discussed. There will be special reference to how these viruses exploit and contribute to pathology in the oral cavity. Reactivation does not necessarily imply clinical symptoms, as reflected in the asymptomatic shedding of EBV and CMV from oral mucosa. The immune response and the level of viral output are both important to the consequences experienced.
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影响因子:
8.8
作者:
Fishman, J. A.
通讯作者:
Fishman, J. A.
DOI:
10.3390/v3050561
发表时间:
2011-05
期刊:
Viruses
影响因子:
--
作者:
Lindemann D;Rethwilm A
通讯作者:
Rethwilm A
影响因子:
10.5
作者:
Kobayashi, Mariko;Wilson, Angus C.;Mohr, Ian
通讯作者:
Mohr, Ian
影响因子:
5.9
作者:
Hillaire, M. L. B.;Rimmelzwaan, G. F.;Kreijtz, J. H. C. M.
通讯作者:
Kreijtz, J. H. C. M.
影响因子:
64.8
作者:
Barton, Erik S.;White, Douglas W.;Virgin, Herbert W.
通讯作者:
Virgin, Herbert W.