Context effects in the formation of deletions in Escherichia coli.
Context effects in the formation of deletions in Escherichia coli.
复制标题
大肠杆菌缺失形成的背景效应。
DOI:
10.1093/genetics/126.1.17
复制
发表时间:
1990
期刊:
影响因子:
3.3
通讯作者:
Berg,DE
中科院分区:
文献类型:
--
作者:
Kazic,T;Berg,DE
We have examined the frequency with which identical deletions are formed in different chromosomal contexts. A panel of six mutant bla genes containing palindrome/direct repeat structures were moved from pBR322 to three locations: at lambda att, at chromosomal lac, and at F'lac. Deletion of the palindromes and one of the direct repeats results in reversion to Ampr. The frequency of deletion for all alleles declines beyond the reduction in copy number when they are moved from the multicopy plasmid environment to a single-copy chromosome. The magnitude of the declines varies in an allele-specific and location-specific manner. Our data support the hypothesis that context can influence the frequency of mutation independent of the immediate DNA sequence.
登录
查看更多内容
影响因子:
2.6
作者:
Ad A.C.M. Peijnenburg;Piet V. Breed;S. Bron;Gerard Venema
通讯作者:
Gerard Venema
影响因子:
3.5
作者:
COVARRUBIAS, L;CERVANTES, L;BOLIVAR, F
通讯作者:
BOLIVAR, F
DOI:
10.1073/pnas.78.1.459
发表时间:
1981-01-01
期刊:
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES
影响因子:
--
作者:
EGNER, C;BERG, DE
通讯作者:
BERG, DE
DOI:
--
发表时间:
2022
期刊:
影响因子:
--
作者:
Barrett;B;Ohta;H.;and Trencher;G. "Prospects for Acceleration of Socio-Technical Transitions for Deep Decarbonization," pp. 400-414;青山瑠妙;福田円;舒旻「中国:EUとの脆弱な相互依存」pp. 247-271;福田円;青山瑠妙;青山瑠妙;青山瑠妙;福田円;青山瑠妙;福田円
通讯作者:
福田円
影响因子:
3.2
作者:
B. Michel;E. d’Alençon;S. Ehrlich
通讯作者:
S. Ehrlich