Lack of cortical contrast gain control in human photosensitive epilepsy
Lack of cortical contrast gain control in human photosensitive epilepsy
复制标题
人类光敏性癫痫缺乏皮质对比增益控制
作者：
V. Porciatti;P. Bonanni;A. Fiorentini;R. Guerrini
电视和视频游戏可能是视觉诱发癫痫发作的强大触发器。为了更好地了解视觉刺激的触发因素和皮质机制的过度兴奋，我们检查了11例特发性光敏性癫痫患者记录视觉诱发电位（VEP）的时间调制模式的不同对比度。对于低-中，但不是高，时间频率的刺激，VEP振幅和潜伏期的对比度依赖性是显着异常的亮度对比度（黑白），但不是这样的彩色对比度（等亮度红-绿）刺激。我们的结论是，相对较低的时间频率和高亮度对比度的模式刺激的对比度增益控制的皮层机制缺乏或严重受损的感光主体。
Television and video games may be powerful triggers for visually induced epileptic seizures. To better understand the triggering elements of visual stimuli and cortical mechanisms of hyperexcitability, we examined eleven patients with idiopathic photosensitive epilepsy by recording visually evoked potentials (VEPs) in response to temporally modulated patterns of different contrast. For stimuli of low–medium, but not high, temporal frequency, the contrast dependence of VEP amplitude and latency is remarkably abnormal for luminance contrast (black–white), but not so for chromatic contrast (equiluminant red–green) stimuli. We conclude that cortical mechanisms of contrast gain control for pattern stimuli of relatively low temporal frequency and high luminance contrast are lacking or severely impaired in photosensitive subjects.
对比度增益控制如何改变猫视网膜神经节细胞的频率响应。
DOI：
10.1113/jphysiol.1981.sp013856
发表时间：
1981
期刊：
The Journal of physiology
影响因子：
--
作者：
Shapley,RM;Victor,JD
通讯作者：
Victor,JD
影响因子：
56.9
作者：
CARANDINI, M;HEEGER, DJ
通讯作者：
HEEGER, DJ