Bioinspired surface hierarchical microstructures of Ti6Al4V alloy with a positive effect on osteoconduction
Bioinspired surface hierarchical microstructures of Ti6Al4V alloy with a positive effect on osteoconduction
复制标题
Ti6Al4V合金的仿生表面分级微观结构对骨传导有积极作用
DOI:
10.1016/j.surfcoat.2020.125594
复制
发表时间:
2020-04
影响因子:
5.4
通讯作者:
Guanghua Cheng
中科院分区:
文献类型:
--
作者:
Chen Li;Lijun Yang;Nan Liu;Yong Yang;Jing Zhao;Pengfei Yang;Guanghua Cheng
Osteoconduction is critical for the success of dental and orthopaedic implants. Inspired by the remarkable adhesion of the skin structures in tree frog toe pads, biomimetic hierarchical surface structures on titanium alloy implants are fabricated by laser surface texturing and chemistry surface treatment in this work, to improve osteoconduction on implants. The main differences in the wettability, bioactivity in simulated body fluid and osteoblastic cell MC3T3 proliferation were measured and analyzed among Ti6Al4V samples with smooth surface, micro-hexagons and hierarchical structures, respectively. Noteworthy, bioinspired hierarchical structures displayed the lowest contact angle in hydrophilicity, best bioactivity and excellent cell proliferation. The reasons for these differences were found and discussed in the topographical cues and bioactive surface layer. An innovative functionalization strategy of improving the osteoconduction on titanium alloy implants was proposed using the hierarchical structures, which is meaningful in various tissue engineering applications and implant fields.
登录
查看更多内容
DOI:
10.1007/978-3-642-56486-4_11
发表时间:
2001
期刊:
--
影响因子:
--
作者:
N. Jaeger;D. Brunette
通讯作者:
N. Jaeger;D. Brunette
影响因子:
3.9
作者:
Federle, W.;Barnes, W. J. P.;Smith, J. M.
通讯作者:
Smith, J. M.
DOI:
10.1088/1361-6463/ab5df7
发表时间:
2019-12
期刊:
Journal of Physics D: Applied Physics
影响因子:
--
作者:
Chen Li;Lijun Yang;Xuezhuang Ren;Yong Yang;G. Cheng
通讯作者:
Chen Li;Lijun Yang;Xuezhuang Ren;Yong Yang;G. Cheng
DOI:
10.1002/jbm.a.30013
发表时间:
2004-06
期刊:
Journal of biomedical materials research. Part A
影响因子:
--
作者:
R. Stangl;A. Pries;B. Loos;M. Müller;R. Erben
通讯作者:
R. Stangl;A. Pries;B. Loos;M. Müller;R. Erben
影响因子:
4.3
作者:
Z. Schwartz;Z. Schwartz;C. H. Lohmann;C. H. Lohmann;M. Wieland;David L. Cochran;David D Dean;M. Textor;L. F. Bonewald;B. Boyan
通讯作者:
Z. Schwartz;Z. Schwartz;C. H. Lohmann;C. H. Lohmann;M. Wieland;David L. Cochran;David D Dean;M. Textor;L. F. Bonewald;B. Boyan