FDG-PET in infectious lesions: The detection and assessment of lesion activity
FDG-PET in infectious lesions: The detection and assessment of lesion activity
复制标题
FDG-PET 在感染性病变中：病变活动的检测和评估
作者：
Y. Ichiya;Y. Kuwabara;M. Sasaki;Tsuyoshi Yoshida;Y. Akashi;S. Murayama;Katsumasa Nakamura;T. Fukumura;K. Masuda
评价FDG-PET在检测感染灶和评估病变活动性方面的有用性。该研究涵盖了24名患者的25项FDG-PET研究，包括细菌、结核和真菌来源的病变。FDG摄取由静态图像上的病变与肌肉的比率（LMR）确定。时间活性曲线（TAC）分为四种模式的基础上存在的初始峰和斜率之后。在25个病灶中的23个（92%）中观察到高FDG摄取。两个病变，其中没有异常摄取，包括一个在愈合阶段，另一个由一个薄壁腔。急性活动性病变的LMR高于慢性活动性或愈合性病变（平均值± SD：分别为9.8 ± 3.6、3.6 ± 1.8和4.3 ± 1.7，p <0.05），并且可以通过LMR 6大致区分。急性或慢性活动性病变的TAC模式是增加而无初始峰值或平台，而愈合病变中的TAC模式主要表现为增加而有初始尖峰。我们的研究结果表明，FDG-PET在临床上是有用的检测各种微生物的感染，以及在病变活动的评估。
The usefulness of FDG-PET in the detection of infectious foci and the assessment of lesion activity was evaluated. The study covered 24 patients with 25 FDG-PET studies, including lesions of bacterial, tuberculous and fungal origins. The FDG uptake was determined by the lesion to muscle ratio (LMR) on the static images. The time activity curves (TACs) were classified into four patterns based on both the existence of an initial peak and a slope thereafter. A high FDG uptake was observed in 23 of 25 lesions (92%). Two lesions, in which no abnormal uptake was noted, included one in the healing stage and the other consisting of a cavity with a thin wall. The acute active lesions showed higher LMRs than the chronic active or healing lesions (mean ± SD: 9.8 ± 3.6, 3.6 ±1.8 and 4.3 ± 1.7, respectively, p < 0.05), and they could be approximately distinguished by an LMR of 6. The patterns of the TACs in acute or chronic active lesions were either an increase without an initial peak or a plateau, while those in the healing lesions demonstrated predominantly an increase with an initial sharp peak. Our results indicated that FDG-PET is clinically useful in the detection of the infection of miscellaneous microorganisms as well as in the assessment of lesion activity.
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影响因子：
19.7
作者：
WAHL, RL;QUINT, LE;ORRINGER, MB
通讯作者：
ORRINGER, MB
DOI：
--
发表时间：
1991-04
期刊：
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
影响因子：
--
作者：
L. Strauss;P. Conti
通讯作者：
L. Strauss;P. Conti
In-111 白细胞成像的临床应用。
影响因子：
10.6
作者：
Goodwin,DA
通讯作者：
Goodwin,DA
受损组织中的葡萄糖代谢：一项纵向研究。
影响因子：
3.8
作者：
Daley,JM;Shearer,JD;Mastrofrancesco,B;Caldwell,MD
通讯作者：
Caldwell,MD