Enhanced phase synchronization of blood flow oscillations between heated and adjacent non-heated sacral skin.
Enhanced phase synchronization of blood flow oscillations between heated and adjacent non-heated sacral skin.
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DOI：
10.1007/s11517-012-0948-y
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发表时间：
2012-10
影响因子：
3.2
通讯作者：
Jan, Yih-Kuen
中科院分区：
文献类型：
--
作者：
Liao, Fuyuan;Jan, Yih-Kuen
关键词：
皮肤微循环的研究可用于评估压疮的风险。观察到，局部加热不仅会导致受热皮肤的血流量增加，而且还会导致邻近未受热皮肤的血流量增加。这种非加热皮肤间接血管扩张的潜在生理机制尚不清楚。我们假设，邻近非加热皮肤区域的血流振荡(BFO)与加热皮肤中的BFO同步，从而引发血管扩张反应。我们研究了12名健康受试者骶骨受热皮肤和邻近非受热皮肤(距离12.1±1.2 cm)中的BFO。利用集成经验模式分解将血流信号分解为一组本征模式函数，选择功率谱在0.0095.0 2~0.0 2、0.0 2~0.0 5、0.0 5~0.15 Hz范围内的固有模式函数分别作为代谢、神经源性和肌源性调节的特征分量。然后，利用希尔伯特变换计算特征分量的瞬时相位。从一对特征分量之间的相位差时间序列中，检测出相位同步的历元。结果表明，在加热皮肤的缓慢扩张过程中，肌源性和神经源性BFO表现出自身时相同步。在非加热皮肤中，BFO的同步化程度与血液流动的变化有关。
The study of skin microcirculation may be used to assess risk for pressure ulcers. It is observed that local heating not only causes an increase in blood flow of the heated skin but also in the adjacent non-heated skin. The underlying physiological mechanism of this indirect vasodilation of the non-heated skin remains unclear. We hypothesized that blood flow oscillations (BFO) in the adjacent non-heated skin area synchronize with BFO in the heated skin, thus inducing a vasodilatory response. We investigated BFO in the heated and adjacent non-heated skin (12.1±1.2 cm distance) on the sacrum in 12 healthy participants. The ensemble empirical mode decomposition (EEMD) was used to decompose blood flow signals into a set of intrinsic mode functions (IMFs), and the IMFs with power spectra over the frequency range of 0.0095–0.02 Hz, 0.02–0.05 Hz, and 0.05–0.15 Hz were chosen as the characteristic components corresponding to metabolic, neurogenic, and myogenic regulations, respectively. Then, the instantaneous phase of the characteristic components was calculated using the Hilbert transform. From the time series of phase difference between a pair of characteristic components, the epochs of phase synchronization were detected. The results showed that myogenic and neurogenic BFO exhibit self-phase synchronization during the slower vasodilation of the heated skin. In the non-heated skin, the degree of synchronization of BFO is associated with the changes in blood flow.
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影响因子：
3.1
作者：
Bernjak, A.;Deitrick, G. A.;Tuckman, J.
通讯作者：
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影响因子：
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作者：
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Minson, Christopher T.
DOI：
10.1016/j.apmr.2007.07.046
发表时间：
2008-01-01
影响因子：
4.3
作者：
Jan, Yih-Kuen;Brienza, David M.;Karg, Patricia
通讯作者：
Karg, Patricia