The ultrastructural organization and architecture of basement membranes.

The ultrastructural organization and architecture of basement membranes.
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基底膜的超微结构组织和结构。

DOI:
10.1002/9780470720899.ch2
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发表时间:
1984
期刊:
Ciba Foundation symposium
影响因子:
--
通讯作者:
Furthmayr,H
Furthmayr,H
中科院分区:
--
文献类型:
--
作者:
Madri,JA;Pratt,BM;Yurchenco,PD;Furthmayr,H

文献摘要

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基底膜是普遍存在的具有不同功能的复杂的多组分结构。它们在形态上是不同的,并表现出特定的结构细节,包括板罕见和致密。另外。与致密板邻接的间质基质具有独特的组织结构。而基底膜的组成至今仍不完全清楚。已经确定了几个组成部分。包括IV型和V型胶原蛋白、层粘连蛋白和硫酸乙酰肝素蛋白聚糖。高分辨率免疫电镜研究已经允许发展基底膜的组织和结构的各种模型,表明各种胶原类型和胶原分子、层粘连蛋白和其他组分的特定结构域的特定定位。另外。高分辨率的金属阴影投射技术已经允许开发基底膜的特定组分的分子模型以及研究这些组分的域结构和相互作用的方法。
Basement membranes are ubiquitous complex, multicomponent structures having diverse functions. They are morphologically distinct and exhibit specific structural details including the lamina rara and lamina densa. In addition. the interstitial stroma abutting the lamina densa has a unique organization. While the composition of basement membranes is still incompletely known. several components have been identified. including collagen types IV and V. laminin and heparan sulphate proteoglycan. High resolution immunoelectrori microscopic studies have allowed the development of various models of the organization and architecture of the basement membrane, suggesting specific localizations of the various collagen types and specific domains ot the collagen molecules, laminin and other components. In addition. high resolution metal shadow casting techniques have allowed the development of molecular models of specific components of the basement membrane and methods of studying the domain structure and interactions of these components.
结缔组织大分子的旋转阴影。
DOI: 10.1016/s0174-173x(82)80025-3
发表时间: 1982
期刊: Collagen and related research
影响因子: --
作者:
Furthmayr,H;Madri,JA
通讯作者: Madri,JA
DOI: --
发表时间: 1983
期刊: Laboratory investigation; a journal of technical methods and pathology
影响因子: --
作者:
Foellmer,HG;Madri,JA;Furthmayr,H
通讯作者: Furthmayr,H
DOI: --
发表时间: 1983
影响因子: 3.6
作者:
Cohen,CM
通讯作者: Cohen,CM
迁移表皮产生AB2胶原蛋白,需要持续合成胶原蛋白才能运动
DOI: --
发表时间: 1979
期刊: Nature
影响因子: 64.8
作者:
K. Stenn;Joseph A. Madri;F. Roll
通讯作者: F. Roll
DOI: --
发表时间: 1981-05
期刊: The Journal of biological chemistry
影响因子: --
作者:
B. Carlin;R. Jaffe;B. Bender;A. Chung
通讯作者: B. Carlin;R. Jaffe;B. Bender;A. Chung