Cardiac Myxomas Show Elevated Native T1, T2 Relaxation Time and ECV on Parametric CMR.
Cardiac Myxomas Show Elevated Native T1, T2 Relaxation Time and ECV on Parametric CMR.
复制标题
心脏粘液瘤显示了参数CMR的天然T1，T2松弛时间和ECV。
DOI：
10.3389/fcvm.2020.602137
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发表时间：
2020
影响因子：
3.6
通讯作者：
Kelle S
中科院分区：
文献类型：
--
作者：
Nasser SB;Doeblin P;Doltra A;Schnackenburg B;Wassilew K;Berger A;Gebker R;Bigvava T;Hennig F;Pieske B;Kelle S
引言：虽然心脏肿瘤是罕见的，他们的识别和分化具有广泛的临床意义。最近的心脏磁共振（CMR）参数映射技术允许定量组织表征。我们的目的是检查心脏粘液瘤中遇到的与组织学测量相关的数值范围。方法和结果：9例经组织学证实的心脏粘液瘤患者纳入研究。术前对所有患者进行CMR（1.5 T，Philips），包括参数标测。所有数据报告为平均值±标准差。与心肌相比，心脏粘液瘤表现出更高的天然T1弛豫时间（1，554 ± 192 ms vs. 1，017 ± 58 ms，p < 0.001）、ECV（46.9 ± 13.0% vs. 27.1 ± 2.6%，p = 0.001）和T2弛豫时间（209 ± 120 ms vs. 52 ± 3 ms，p = 0.008）。有LGE的地区比没有LGE的地区表现出更高的ECV（54.3 ± 17.8% vs. 32.7 ± 18.6%，p = 0.042），天然T1弛豫时间存在差异（1，644 ± 217 ms与1，482 ± 351 ms，p = 0.291）和T2弛豫时间（356 ± 236 ms与129 ± 68 ms，p = 0.155）未达到统计学显著性。结论：参数CMR显示，与正常心肌相比，心脏粘液瘤的T1和T2弛豫时间和ECV值升高，反映了间质空间和液体含量增加。这可能有助于心脏粘液瘤与其他肿瘤实体的鉴别。
Introduction: While cardiac tumors are rare, their identification and differentiation has wide clinical implications. Recent cardiac magnetic resonance (CMR) parametric mapping techniques allow for quantitative tissue characterization. Our aim was to examine the range of values encountered in cardiac myxomas in correlation to histological measurements. Methods and Results: Nine patients with histologically proven cardiac myxomas were included. CMR (1.5 Tesla, Philips) including parametric mapping was performed in all patients pre-operatively. All data are reported as mean ± standard deviation. Compared to myocardium, cardiac myxomas demonstrated higher native T1 relaxation times (1,554 ± 192 ms vs. 1,017 ± 58 ms, p < 0.001), ECV (46.9 ± 13.0% vs. 27.1 ± 2.6%, p = 0.001), and T2 relaxation times (209 ± 120 ms vs. 52 ± 3 ms, p = 0.008). Areas with LGE showed higher ECV than areas without (54.3 ± 17.8% vs. 32.7 ± 18.6%, p = 0.042), with differences in native T1 relaxation times (1,644 ± 217 ms vs. 1,482 ± 351 ms, p = 0.291) and T2 relaxation times (356 ± 236 ms vs. 129 ± 68 ms, p = 0.155) not reaching statistical significance. Conclusions: Parametric CMR showed elevated native T1 and T2 relaxation times and ECV values in cardiac myxomas compared to normal myocardium, reflecting an increased interstitial space and fluid content. This might help in the differentiation of cardiac myxomas from other tumor entities.
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DOI：
10.1161/circimaging.111.967836
发表时间：
2012-01
期刊：
Circulation. Cardiovascular imaging
影响因子：
--
作者：
Thavendiranathan P;Walls M;Giri S;Verhaert D;Rajagopalan S;Moore S;Simonetti OP;Raman SV
通讯作者：
Raman SV
影响因子：
39.3
作者：
Fussen, Sandra;De Boeck, Bart W. L.;Buser, Peter T.
通讯作者：
Buser, Peter T.
DOI：
10.1186/s12968-017-0389-8
发表时间：
2017-10-09
期刊：
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
影响因子：
--
作者：
Messroghli DR;Moon JC;Ferreira VM;Grosse-Wortmann L;He T;Kellman P;Mascherbauer J;Nezafat R;Salerno M;Schelbert EB;Taylor AJ;Thompson R;Ugander M;van Heeswijk RB;Friedrich MG
通讯作者：
Friedrich MG
影响因子：
5.9
作者：
Bauner, K. U.;Sourbron, S.;Huber, A. M.
通讯作者：
Huber, A. M.
影响因子：
4.8
作者：
Pucci, A;Gagliardotto, P;Mollo, F
通讯作者：
Mollo, F