Diagnosis and treatment of a carotid body tumor: A case report of a rare bilateral tumor.

Diagnosis and treatment of a carotid body tumor: A case report of a rare bilateral tumor.
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颈动脉体肿瘤的诊治:罕见双侧肿瘤一例报告

DOI:
10.3892/ol.2017.7101
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发表时间:
2017-12
期刊:
影响因子:
2.9
通讯作者:
Sun M
Sun M
中科院分区:
医学4区
文献类型:
--
作者:
Sun Q;Xie C;Niu Z;Su L;Wang X;Fang Z;Zhao J;Chen S;Li X;Sun M

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本文报告一种罕见的双侧颈动脉体瘤(CBT)及其影像和病理特征。本文对1例罕见的双侧颈总动脉分叉部颈动脉体瘤的临床表现、影像及病理特点进行了总结。影像不能确认诊断,但影像显示肿瘤的包膜是完整的。免疫组织化学染色显示,肿瘤细胞分化簇56、Syn和S-100蛋白呈强阳性,转录因子E3呈中等阳性,细胞角蛋白和上皮膜抗原阴性,部分细胞Desmir呈弱阳性(5%)。鉴于颈动脉体瘤的临床和病理特点,手术被认为是最好的治疗方法,并有可能使肿瘤完全切除。精致的手术技术提供了安全切除的安全性,并降低了并发症发生的风险。
In the present case report, a rare bilateral carotid body tumor (CBT) and the imaging and pathological features of a CBT are described. In the present report, a rare case of bilateral carotid body tumor, which developed in the bifurcation of the common carotid artery, and the clinical manifestations, imaging and pathological features of this CBT are summarized. The imaging cannot validate the diagnosis; however, imaging identified that the tumor exhibited an intact envelope. Immunohistochemical staining revealed that the tumor cells were strongly positive for cluster of differentiation 56, Syn and protein S-100, moderately positive for transcription factor E3, negative for cytokeratin and epithelial membrane antigen, and partial cells were weakly positive for Desmir (<5%). In view of the clinical and pathological features of the carotid body tumor, surgery is hypothesized to be the optimal treatment and may enable the tumor to be resected completely. Refined surgical techniques provide the security of safe resection and decrease the risk of complications occurring.
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