The waves that make the pattern: a review on acoustic manipulation in biomedical research.
The waves that make the pattern: a review on acoustic manipulation in biomedical research.
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形成模式的波：生物医学研究中的声学操纵综述。
DOI：
10.1016/j.mtbio.2021.100110
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发表时间：
2021-03
期刊：
影响因子：
--
通讯作者：
Serra T
中科院分区：
文献类型：
--
作者：
Guex AG;Di Marzio N;Eglin D;Alini M;Serra T
人们越来越多地认为，结合技术、生物材料设计和尖端细胞培养的新方法可以推动组织工程和再生医学领域的发展。在这种背景下，在过去十年中，远程控制载体矩阵内的空间细胞组织的声学操纵已成为一种特别有前途的方法。声学或声音诱导的操纵利用驻波对液体介质内的颗粒系统施加的流体动力。无机或有机颗粒、细胞或类器官在驻波的节点内聚集，根据所施加的频率和振幅创建不同的图案。声学操纵已经从二维微米或纳米粒子排列发展到将多种细胞类型或类器官组装成高度复杂的体外组织。在这篇综述中，我们讨论了声学操纵领域过去的研究成果，特别强调生物医学应用。我们调查了微流体、开放室和高通量设备在缓冲液或水凝胶中排列非生命和生命单元的适用性。我们还研究了不同方法带来的挑战及其前景，以更深入地了解体外组织形成及其在生物医学工程领域的应用。回顾了声波在空间上控制颗粒系统的工作。表面声波、体声波和法拉第波的分类。声音可用于排列、分离或过滤聚合物颗粒。声音可以在 3D 中塑造细胞图案以诱导形态发生。长期施加声音会诱导分化和组织形成。
Novel approaches, combining technology, biomaterial design, and cutting-edge cell culture, have been increasingly considered to advance the field of tissue engineering and regenerative medicine. Within this context, acoustic manipulation to remotely control spatial cellular organization within a carrier matrix has arisen as a particularly promising method during the last decade. Acoustic or sound-induced manipulation takes advantage of hydrodynamic forces exerted on systems of particles within a liquid medium by standing waves. Inorganic or organic particles, cells, or organoids assemble within the nodes of the standing wave, creating distinct patterns in response to the applied frequency and amplitude. Acoustic manipulation has advanced from micro- or nanoparticle arrangement in 2D to the assembly of multiple cell types or organoids into highly complex in vitro tissues. In this review, we discuss the past research achievements in the field of acoustic manipulation with particular emphasis on biomedical application. We survey microfluidic, open chamber, and high throughput devices for their applicability to arrange non-living and living units in buffer or hydrogels. We also investigate the challenges arising from different methods, and their prospects to gain a deeper understanding of in vitro tissue formation and application in the field of biomedical engineering. Work on sound waves to spatially control particulate systems is reviewed. Classification of surface acoustic waves, bulk acoustic waves, and Faraday waves. Sound can be used to arrange, separate, or filter polymer particles. Sound can pattern cells in 3D to induce morphogenesis. Long-term applied sound induces differentiation and tissue formation.
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DOI：
10.1016/j.mattod.2015.05.002
发表时间：
2015-12
期刊：
Materials today (Kidlington, England)
影响因子：
--
作者：
Asghar W;El Assal R;Shafiee H;Pitteri S;Paulmurugan R;Demirci U
通讯作者：
Demirci U
影响因子：
4
作者：
Comeau, Eric S.;Hocking, Denise C.;Dalecki, Diane
通讯作者：
Dalecki, Diane
影响因子：
8.6
作者：
Binks, D;Westra, MT;van de Water, W
通讯作者：
van de Water, W
影响因子：
15.1
作者：
Devendran, Citsabehsan;Carthew, James;Neild, Adrian
通讯作者：
Neild, Adrian
影响因子：
29.4
作者：
Chen, Pu;Luo, Zhengyuan;Gueven, Sinan;Tasoglu, Savas;Ganesan, Adarsh Venkataraman;Weng, Andrew;Demirci, Utkan
通讯作者：
Demirci, Utkan