Native microbiota shape insect vector competence for human pathogens.

Native microbiota shape insect vector competence for human pathogens.
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DOI:
10.1016/j.chom.2011.09.006
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发表时间:
2011-10-20
影响因子:
30.3
通讯作者:
Dimopoulos G
Dimopoulos G
中科院分区:
医学1区
文献类型:
--
作者:
Cirimotich CM;Ramirez JL;Dimopoulos G

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昆虫媒介的常驻微生物群可以阻止人类病原体的传播。最近的研究强调了内源性细菌通过激活蚊子和采采蝇的免疫反应或直接抑制病原体的发展来减少病毒和寄生虫感染的能力。这些微生物可能被证明是操纵疟疾和其他重要人类病原体媒介能力的有效媒介。
The resident microbiota of insect vectors can impede transmission of human pathogens. Recent studies have highlighted the capacity of endogenous bacteria to decrease viral and parasitic infections in mosquito and tsetse fly vectors by activating their immune responses or directly inhibiting pathogen development. These microbes may prove effective agents for manipulating the vector competence of malaria and other important human pathogens.
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