Effects of high protein, high carbohydrate, and high fat diets on laboratory parameters.

Effects of high protein, high carbohydrate, and high fat diets on laboratory parameters.
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高蛋白、高碳水化合物和高脂肪饮食对实验室参数的影响。

DOI:
10.1080/07315724.1987.10720196
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发表时间:
1987
影响因子:
3.5
通讯作者:
Oexmann,MJ
Oexmann,MJ
中科院分区:
医学4区
文献类型:
--
作者:
Fagan,TC;Oexmann,MJ

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6名正常志愿者在代谢病房中摄入高蛋白、高碳水化合物和高脂肪等热量饮食,每人10天。在高蛋白饮食中,有1~4名受试者血清肌酐、尿素氮、白蛋白和总蛋白均超过正常范围,升高幅度与蛋白质热量百分比直接相关(R分别为0.82、0.62和0.73,P均<0.01)。高蛋白饮食的空腹血糖高于高脂饮食(p<0.01);高碳水化合物饮食的空腹血糖值居中。空腹血糖与饮食中总碳水化合物或简单碳水化合物的百分比均无显著相关性。在美国经常摄入的饮食范围内,实验室数值可能会有很大差异,可能会超过健康人的正常范围。这些变化可能会误导临床医生,并导致进一步的不必要的测试。
Six normal volunteers consumed high protein, high carbohydrate, and high fat isocaloric diets on a metabolic ward for 10 days each. On the high protein diet, serum creatinine, BUN, albumin, and total protein exceeded the normal range in from one to four subjects; the increases were directly related to the percentage of calories derived from protein (R = 0.82, 0.62, and 0.73 respectively; all p less than 0.01). Fasting serum glucose was higher on the high protein diet than on the high fat diet (p less than 0.01); values on the high carbohydrate diet were intermediate. Fasting serum glucose was not significantly related to the percentage of either total carbohydrates or simple carbohydrates in the diet. Within the range of diets frequently ingested in the United States, laboratory values can vary significantly and can exceed the normal ranges in healthy individuals. These variations may mislead clinicians and lead to further unnecessary tests.
DOI: 10.1093/jn/105.4.428
发表时间: 1975-01-01
影响因子: 4.2
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