Directional associations between cannabis use and anxiety symptoms from late adolescence through young adulthood.
Directional associations between cannabis use and anxiety symptoms from late adolescence through young adulthood.
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DOI：
10.1016/j.drugalcdep.2022.109704
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发表时间：
2022-12-01
影响因子：
4.2
通讯作者：
D'Amico, Elizabeth J.
中科院分区：
文献类型：
--
作者：
Davis, Jordan P.;Pedersen, Eric R.;Tucker, Joan S.;Prindle, John;Dunbar, Michael S.;Rodriguez, Anthony;Seelam, Rachana;D'Amico, Elizabeth J.
关键词：
两个主要理论有助于解释焦虑和大麻使用之间的联系：症状驱动途径(焦虑加剧先于大量使用大麻)和物质诱导途径(更多使用之前焦虑加剧)。虽然大麻使用和焦虑症状同时出现是众所周知的，但对青少年发育过程中大麻使用和焦虑症状的时间顺序知之甚少。数据来自一项正在进行的纵向队列研究。所有前瞻性分析都使用了第8波的数据，当时参与者的年龄在17岁到20岁之间，到第13波，参与者的年龄在21岁到24岁之间(N=2995)。数据建立在加速纵向设计中，我们估计了从17岁到24岁焦虑和大麻使用之间的一系列潜在差异得分模型。男性和女性的模特估计是分开的。对于整个样本和男性来说，更多的大麻使用预示着随后焦虑的增加更多；然而，更严重的焦虑症状与减少大麻使用有关。对于女性来说，结果要复杂得多。先前的、特质样的焦虑水平预测焦虑症状的更大变化(增加)之间存在正相关。然而，当根据先前的变化预测变化时，我们看到最近经历焦虑增加的女性的大麻使用量减少。这项研究的一组细微差别的结果支持焦虑症状和大麻使用之间的动态相互作用，并观察到重要的性别差异。总体而言，我们的结果为重新思考我们的指导理论铺平了道路，包括一个更强大、更灵活和更动态的模型，用于理解物质使用和心理健康症状之间的关系，在发展的关键时期。
Two major theories aid in explaining the association between anxiety and cannabis use: a symptom-driven pathway (heightened anxiety precedes greater cannabis use) and a substance-induced pathway (greater use precedes heightened anxiety). Although the co-occurrence of cannabis use and anxiety symptomology is well-established, less is known about the temporal sequence of cannabis use and anxiety symptomology over the course of young adult development. Data are from an ongoing, longitudinal, cohort study. All prospective analyses used data from wave 8, when participants were between the ages of 17 and 20, through wave 13, when participants are between ages 21 and 24 (N = 2,995). Data were set up in accelerated longitudinal design in which we estimated a series of latent difference score models between anxiety and cannabis use from 17 to 24 years old. Models were estimated for men and women, separately. For the overall sample and men, greater cannabis use predicted greater subsequent increases in anxiety; however, greater anxiety symptoms were associated with decreasing cannabis use. For women, results were more complex. A positive association was noted between prior, trait-like levels of anxiety predicting greater change (increasing) in anxiety symptomology. However, when change is predicted by prior change we see that cannabis use decreases among women who have recently experienced an increase in anxiety. The nuanced set of results from this study support a dynamic interplay between anxiety symptoms and cannabis use, with important sex differences observed. Overall, our results pave the way for rethinking our guiding theories to include a more robust, flexible, and dynamic model for understanding associations between substance use and mental health symptomology during a key period of development.
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影响因子：
4.8
作者：
McLean CP;Asnaani A;Litz BT;Hofmann SG
通讯作者：
Hofmann SG
DOI：
10.1016/j.jaac.2013.09.017
发表时间：
2014-01
影响因子：
13.3
作者：
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影响因子：
6
作者：
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通讯作者：
Patton, George C.
影响因子：
2.7
作者：
van Gastel, W. A.;MacCabe, J. H.;Boks, M. P. M.
通讯作者：
Boks, M. P. M.