Protein SUMOylation and phase separation: partners in stress?
Protein SUMOylation and phase separation: partners in stress?
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DOI:
10.1016/j.tibs.2022.12.003
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发表时间:
2023-05
影响因子:
13.8
通讯作者:
Cheng, Xiaodong
中科院分区:
文献类型:
--
作者:
Cheng, Xiaodong
Protein SUMOylation is one of the most prevalent post-translational modifications (PTMs) and important for maintaining cellular homeostasis in response to various cellular stresses. Emerging evidence reveals the role of liquid-liquid phase separation (LLPS)/biomolecular condensates in cellular SUMOylation, potentially solving a puzzle regarding the cellular mechanism of SUMOylation regulation.
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