MicroRNAs in adult and embryonic neurogenesis.
MicroRNAs in adult and embryonic neurogenesis.
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DOI：
10.1007/s12017-009-8077-y
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发表时间：
2009
影响因子：
3.5
通讯作者：
Zhao, Xinyu
中科院分区：
文献类型：
--
作者：
Liu, Changmei;Zhao, Xinyu
Neurogenesis is defined as a process that includes the proliferation of neural stem/progenitor cells (NPCs) and the differentiation of these cells into new neurons that integrate into the existing neuronal circuitry. MicroRNAs (miRNAs) are a recently discovered class of small non-protein coding RNA molecules implicated in a wide range of diverse gene regulatory mechanisms. More and more data demonstrate that numerous miRNAs are expressed in a spatially and temporally controlled manners in the nervous system, which suggests that miRNAs have important roles in the gene regulatory networks involved in both brain development and adult neural plasticity. This review summarizes the roles of miRNAs-mediated gene regulation in the nervous system with focus on neurogenesis in both embryonic and adult brains.
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DOI：
10.1634/stemcells.2008-0519
发表时间：
2008-12
期刊：
Stem cells (Dayton, Ohio)
影响因子：
--
作者：
Barkho BZ;Munoz AE;Li X;Li L;Cunningham LA;Zhao X
通讯作者：
Zhao X
影响因子：
82.9
作者：
Eriksson, PS;Perfilieva, E;Gage, FH
通讯作者：
Gage, FH
影响因子：
14.9
作者：
Chen C;Ridzon DA;Broomer AJ;Zhou Z;Lee DH;Nguyen JT;Barbisin M;Xu NL;Mahuvakar VR;Andersen MR;Lao KQ;Livak KJ;Guegler KJ
通讯作者：
Guegler KJ
影响因子：
48
作者：
Gentner, Bernhard;Schira, Giulia;Naldini, Luigi
通讯作者：
Naldini, Luigi
影响因子：
64.5
作者：
CHALFIE, M;HORVITZ, HR;SULSTON, JE
通讯作者：
SULSTON, JE