Frailty and type of death among older adults in China: prospective cohort study.
Frailty and type of death among older adults in China: prospective cohort study.
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DOI：
10.1136/bmj.b1175
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发表时间：
2009-04-09
期刊：
影响因子：
--
通讯作者：
Yi Z
中科院分区：
文献类型：
--
作者：
Dupre ME;Gu D;Warner DF;Yi Z
目的探讨中国老年人死亡类型与体弱的关系。设计前瞻性队列研究。设定2002年和2005年两波中国健康长寿纵向调查，在全国22个省份进行。参与者13717名老年人（年龄≥65岁）。主要结果测量死亡类型，分类为卧床不起少于30天，有或没有痛苦，卧床不起30天或更长时间，有或没有痛苦。结果多项分析显示，虚弱程度越高，各种类型死亡的相对死亡危险比越高。在那些虚弱程度最高的人中，男性最有可能在死亡前经历30天或更长时间的卧床不起（相对风险比8.70，95%置信区间6.31至12.00），女性最有可能在30天或更长时间的卧床不起（11.53，17.84至16.96）。无论虚弱与否，百岁老人和九十岁老人最有可能经历不到30天的卧床不起，而65-79岁和80-89岁的人更有可能经历不到30天的卧床不起。调整组成差异对性别和年龄组的虚弱和死亡类型之间的联系几乎没有影响。结论虚弱和死亡类型之间的关联因性别和年龄而异。健康学者和临床医生应该考虑虚弱的年龄和性别差异，以制定更有效的措施来减少死亡前可预防的痛苦。
Objective To examine the association between frailty and type of death among the world’s largest oldest-old population in China. Design Prospective cohort study. Setting 2002 and 2005 waves of the Chinese longitudinal healthy longevity survey carried out in 22 provinces throughout China. Participants 13 717 older adults (aged ≥65). Main outcome measures Type of death, categorised as being bedridden for fewer than 30 days with or without suffering and being bedridden for 30 or more days with or without suffering. Results Multinomial analyses showed that higher levels of frailty significantly increased the relative risk ratios of mortality for all types of death. Of those with the highest levels of frailty, men were most likely to experience 30 or more bedridden days with suffering before death (relative risk ratio 8.70, 95% confidence interval 6.31 to 12.00) and women 30 or more bedridden days with no suffering (11.53, 17.84 to 16.96). Regardless of frailty, centenarians and nonagenarians were most likely to experience fewer than 30 bedridden days with no suffering, whereas those aged 65-79 and 80-89 were more likely to experience fewer than 30 bedridden days with suffering. Adjusting for compositional differences had little impact on the link between frailty and type of death for both sexes and age groups. Conclusions The association between frailty and type of death differs by sex and age. Health scholars and clinical practitioners should consider age and sex differences in frailty to develop more effective measures to reduce preventable suffering before death.
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影响因子：
3.8
作者：
Bookwala, J;Coppola, KM;Smucker, WD
通讯作者：
Smucker, WD
影响因子：
--
作者：
Cohen, LM;Germain, MJ;Kjellstrand, CM
通讯作者：
Kjellstrand, CM
DOI：
10.1093/gerona/60.8.1046
发表时间：
2005-08-01
影响因子：
5.1
作者：
Goggins, WB;Woo, J;Ho, SC
通讯作者：
Ho, SC
DOI：
10.1093/gerona/57.5.m283
发表时间：
2002-05-01
影响因子：
5.1
作者：
Bortz, WM
通讯作者：
Bortz, WM
DOI：
10.1016/j.atc.2005.12.003
发表时间：
2006-03-01
期刊：
ANESTHESIOLOGY CLINICS OF NORTH AMERICA
影响因子：
--
作者：
Gruenewald, DA;White, EJ
通讯作者：
White, EJ