FACS analysis of the planarian stem cell compartment as a tool to understand regenerative mechanisms.
FACS analysis of the planarian stem cell compartment as a tool to understand regenerative mechanisms.
复制标题
对涡虫干细胞室进行 FACS 分析作为了解再生机制的工具。
DOI:
10.1007/978-1-61779-980-8_13
复制
发表时间:
2012
影响因子:
--
通讯作者:
A. Aboobaker
中科院分区:
文献类型:
--
作者:
B. T. Romero;Deborah J. Evans;A. Aboobaker
Planarians provide a relatively simple model system in which to study stem cell dynamics and regenerative phenomena. As with other systems understanding the dynamics of stem cell and stem cell progeny is crucial in order to get at the molecular mechanisms orchestrating stem cell biology. Planarians have an abundant adult stem cell population that can be observed using Fluorescence-Activated Cell Sorting (FACS). This approach allows different subpopulations of stem cells and their progeny to be monitored and sorted for downstream studies in response to different regenerative scenarios, drug treatments, or RNAi knockdown of genes required for regenerative events.
影响因子:
11.8
作者:
Reddien, PW;Bermange, AL;Alvarado, AS
通讯作者:
Alvarado, AS
影响因子:
23.9
作者:
Eisenhoffer, George T.;Kang, Hara;Alvarado, Alejandro Sanchez
通讯作者:
Alvarado, Alejandro Sanchez
影响因子:
2.7
作者:
Wenemoser D;Reddien PW
通讯作者:
Reddien PW