Assessment of feeding behavior in laboratory mice.
Assessment of feeding behavior in laboratory mice.
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DOI:
10.1016/j.cmet.2010.06.001
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发表时间:
2010-07-07
期刊:
影响因子:
29
通讯作者:
Schwartz MW
中科院分区:
文献类型:
--
作者:
Ellacott KL;Morton GJ;Woods SC;Tso P;Schwartz MW
The global obesity epidemic has heightened the need for an improved understanding of how body weight is controlled, and research using mouse models is critical to this effort. In this perspective, we provide a conceptual framework for investigation of feeding behavior in this species, with an emphasis on factors that influence study design, data interpretation, and relevance to feeding behavior in humans. Although we focus on the mouse, the principles presented can be applied to most other animal models. This document represents the current consensus view of investigators from the National Institutes of Health (NIH)-funded Mouse Metabolic Phenotyping Centers (MMPCs).
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