Spatial Distribution of Attentional Modulation at Columnar Resolution in Macaque Area V4.

Spatial Distribution of Attentional Modulation at Columnar Resolution in Macaque Area V4.
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猕猴 V4 区柱状分辨率注意调制的空间分布

DOI:
10.3389/fncir.2016.00102
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发表时间:
2016
影响因子:
3.5
通讯作者:
Roe AW
Roe AW
中科院分区:
医学3区
文献类型:
--
作者:
Tanigawa H;Chen G;Roe AW

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注意视觉场景中的一个位置会以视网膜特异性方式影响视皮层区域的神经元反应。光学成像研究表明,皮层反应由两个不同大小的组件组成:刺激非特异性的全球信号和刺激特异性映射信号(域活动)。目前尚不清楚这两个组成部分中的一个或两个是否受到空间注意的调节。在这项研究中,以确定注意力调制在柱状分辨率的空间分布,我们进行了脑血容量(CBV)为基础的光学成像在V4区的猴子执行颜色变化检测任务,其中空间注意力被操纵。我们发现,空间注意增强了血流动力学反应的全球信号,但不影响刺激选择域活动。这些结果表明,在空间注意的神经处理的整体信号的参与。我们建议,全球信号反映了注意力归一化模型中归一化池的神经基质。
Attention to a location in a visual scene affects neuronal responses in visual cortical areas in a retinotopically specific manner. Optical imaging studies have revealed that cortical responses consist of two components of different sizes: the stimulus-nonspecific global signal and the stimulus-specific mapping signal (domain activity). It remains unclear whether either or both of these components are modulated by spatial attention. In this study, to determine the spatial distribution of attentional modulation at columnar resolution, we performed cerebral blood volume (CBV)-based optical imaging in area V4 of monkeys performing a color change detection task in which spatial attention was manipulated. We found that spatial attention enhanced global signals of the hemodynamic responses, but did not affect stimulus-selective domain activities. These results indicate the involvement of global signals in neural processing of spatial attention. We propose that global signals reflect the neural substrate of the normalization pool in normalization models of attention.
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