Recent developments in yeast aging.
Recent developments in yeast aging.
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DOI:
10.1371/journal.pgen.0030084
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发表时间:
2007-05-25
期刊:
影响因子:
4.5
通讯作者:
Kennedy, Brian K.
中科院分区:
文献类型:
--
作者:
Kaeberlein, Matt;Burtner, Christopher R.;Kennedy, Brian K.
In the last decade, research into the molecular determinants of aging has progressed rapidly and much of this progress can be attributed to studies in invertebrate eukaryotic model organisms. Of these, single-celled yeast is the least complicated and most amenable to genetic and molecular manipulations. Supporting the use of this organism for aging research, increasing evidence has accumulated that a subset of pathways influencing longevity in yeast are conserved in other eukaryotes, including mammals. Here we briefly outline aging in yeast and describe recent findings that continue to keep this “simple” eukaryote at the forefront of aging research.
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期刊:
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通讯作者:
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