Upper airway muscle activity during REM and non-REM sleep of patients with obstructive apnea.
Upper airway muscle activity during REM and non-REM sleep of patients with obstructive apnea.
复制标题
阻塞性呼吸暂停患者快速眼动睡眠和非快速眼动睡眠期间的上呼吸道肌肉活动。
作者：
S. Okabe;W. Hida;Y. Kikuchi;O. Taguchi;T. Takishima;K. Shirato
We measured electromyograms (EMGs) of genioglossus muscle (GG) and inspiratory intercostal muscle (IIM) in both rapid eye movement (REM) sleep and non-REM sleep of 12 patients with obstructive sleep apnea (OSA) to examine the influence of different sleep stages on upper airway muscle activity during sleep apnea. Quantifications of both muscle activities were assessed by their individual peak amplitude of integrated inspiratory EMG. Genioglossus and IIM activities showed a qualitatively similar cyclic change with an alteration of apneic and ventilatory phases during both non-REM and REM sleep. Both muscle activities increased gradually in the late apneic phase and reached each peak at the opening of the upper airway and, subsequently, decreased gradually. There were no significant differences in both muscles activities in either the ventilatory or early apneic phase between non-REM sleep and REM sleep. On the other hand, GG and IIM activities in the late apneic phase during REM sleep were significantly lower than those during non-REM sleep. The relative activity of GG to IIM in the late apneic phase was significantly lower during REM sleep than that during non-REM sleep. These results indicate that upper airway and intercostal muscle activation in the later apneic phase during REM sleep were inhibited compared with those during non-REM sleep and that this inhibition was observed predominantly in upper airway muscles.
睡眠期间颏舌肌和膈肌对高碳酸血症的反应之间的相关性。
DOI：
10.1164/arrd.1987.135.2.378
发表时间：
1987
期刊：
The American review of respiratory disease
影响因子：
--
作者：
Parisi,RA;Neubauer,JA;Frank,MM;Edelman,NH;Santiago,TV
通讯作者：
Santiago,TV
正常男性阶段性快速眼动睡眠期间上呼吸道肌肉激活和通气的变化。
DOI：
10.1152/jappl.1991.71.2.488
发表时间：
1991
期刊：
Journal of applied physiology (Bethesda, Md. : 1985)
影响因子：
--
作者：
Wiegand,L;Zwillich,CW;Wiegand,D;White,DP
通讯作者：
White,DP
睡眠期间缺氧的颏舌肌和膈肌肌电图反应。
DOI：
10.1164/ajrccm/138.3.610
发表时间：
1988
期刊：
The American review of respiratory disease
影响因子：
--
作者：
Parisi,RA;Santiago,TV;Edelman,NH
通讯作者：
Edelman,NH