ELIXIR: providing a sustainable infrastructure for life science data at European scale.
ELIXIR: providing a sustainable infrastructure for life science data at European scale.
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DOI:
10.1093/bioinformatics/btab481
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发表时间:
2021-08-25
期刊:
影响因子:
--
通讯作者:
Blomberg N
中科院分区:
文献类型:
--
作者:
Harrow J;Drysdale R;Smith A;Repo S;Lanfear J;Blomberg N
In 2012, the Digital Universe Study reported that ‘less than 1% of the World’s data is analyzed and less than 20% is protected’and recommended that management plans were needed to harness the potential within these data streams (Gantz and Reinsel, 2012). Life science is a data science that is dependent on the generation, sharing and integrative analysis of vast quantities of digital data. However, these data are complex and fragmented, creating a significant barrier to their integration and reuse. Data are generated for different research purposes at thousands of facilities across the world, with diverse formats, annotations, methodologies and metadata standards. Interpreting this data is difficult and often involves integrating very large datasets from multiple sources. Certain data types such as sensitive human data archived under controlled access require protection, so data federation and sharing are a challenge in this context (Saunders et al., 2019).Since its official launch in December 2013, ELIXIR (https://elixir-europe. org/), the European infrastructure for life science data, has worked to address these challenges by bringing Europe’s national centers and core bioinformatics resources into a single, coordinated infrastructure. Many European countries have longestablished national bioinformatics infrastructures that provide tools, data resources and cloud services to national and international users. ELIXIR invests in and aims to sustain these vital resources and ensure a level of interoperability that facilitates scientific discovery. Indeed, for research to thrive in a world of data abundance, all components (research data, analysis tools, standards as well as computational resources and training materials) must be FAIR—findable, accessible, interoperable and reusable (Wilkinson et al., 2016). ELIXIR supports European life scientists in making data FAIR, ensuring that the benefits extend far beyond those actively participating in ELIXIR, and, additionally, encourages all funders to adopt Open Science mandates.
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影响因子:
2.9
作者:
Haas J;Barbato A;Behringer D;Studer G;Roth S;Bertoni M;Mostaguir K;Gumienny R;Schwede T
通讯作者:
Schwede T
DOI:
10.1093/bioinformatics/btx192
发表时间:
2017-08-15
期刊:
Bioinformatics (Oxford, England)
影响因子:
--
作者:
da Veiga Leprevost F;Grüning BA;Alves Aflitos S;Röst HL;Uszkoreit J;Barsnes H;Vaudel M;Moreno P;Gatto L;Weber J;Bai M;Jimenez RC;Sachsenberg T;Pfeuffer J;Vera Alvarez R;Griss J;Nesvizhskii AI;Perez-Riverol Y
通讯作者:
Perez-Riverol Y
影响因子:
--
作者:
Robertsen, Espen Mikal;Denise, Hubert;Willassen, Nils Peder
通讯作者:
Willassen, Nils Peder
影响因子:
--
作者:
Eijssen, Lars;Evelo, Chris;Hooft, Rob
通讯作者:
Hooft, Rob
影响因子:
9.5
作者:
Gerritsen, Vivienne Baillie;Palagi, Patricia M.;Durinx, Christine
通讯作者:
Durinx, Christine