Dairy augmentation of total and central fat loss in obese subjects
Dairy augmentation of total and central fat loss in obese subjects
复制标题
乳制品可增加肥胖受试者的总脂肪和中心脂肪减少量
DOI:
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发表时间:
2005
影响因子:
4.9
通讯作者:
E. Silva
中科院分区:
文献类型:
--
作者:
M. Zemel;J. Richards;S. Mathis;Anita Milstead;L. Gebhardt;E. Silva
BACKGROUND AND OBJECTIVE: We have previously demonstrated an antiobesity effect of dietary Ca; this is largely mediated by Ca suppression of calcitriol levels, resulting in reduced adipocyte intracellular Ca2+ and, consequently, a coordinated increase in lipid utilization and decrease in lipogenesis. Notably, dairy Ca is markedly more effective than other Ca sources.DESIGN: Obese subjects were placed on balanced deficit (−500 kcal/day) diets and randomized to control (400–500 mg Ca/day; n=16) or yogurt (1100 mg Ca/day; n=18) treatments for 12 weeks. Dietary macronutrients and fiber were held constant at the US average.MEASUREMENTS: Body weight, body fat and fat distribution (by dual-energy X-ray absorptiometry), blood pressure and circulating lipids were measured at baseline and after 12 weeks of intervention.RESULTS: Fat loss was markedly increased on the yogurt diet (−4.43±0.47 vs −2.75±0.73 kg in yogurt and control groups; P<0.005) while lean tissue loss was reduced by 31% on the yogurt diet. Trunk fat loss was augmented by 81% on the yogurt vs control diet (P<0.001), and this was reflected in a markedly greater reduction in waist circumference (−3.99±0.48 vs −0.58±1.04 cm, P<0.001). Further, the fraction of fat lost from the trunk was higher on the yogurt diet vs control (P<0.005).CONCLUSION: Isocaloric substitution of yogurt for other foods significantly augments fat loss and reduces central adiposity during energy restriction.
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影响因子:
4.2
作者:
Heaney, RP
通讯作者:
Heaney, RP
DOI:
10.1210/jcem.85.12.7063
发表时间:
2000-12
期刊:
The Journal of clinical endocrinology and metabolism
影响因子:
--
作者:
K. Davies;R. Heaney;R. Recker;J. Lappe;M. Barger-Lux;K. Rafferty;S. Hinders
通讯作者:
K. Davies;R. Heaney;R. Recker;J. Lappe;M. Barger-Lux;K. Rafferty;S. Hinders
影响因子:
15.9
作者:
Masuzaki, H;Yamamoto, H;Flier, JS
通讯作者:
Flier, JS
DOI:
10.1093/ajcn/74.1.90
发表时间:
2001
期刊:
The American journal of clinical nutrition
影响因子:
--
作者:
Lovejoy,JC;Champagne,CM;Smith,SR;deJonge,L;Xie,H
通讯作者:
Xie,H
DOI:
10.1093/ajcn/77.2.281
发表时间:
2003
期刊:
The American journal of clinical nutrition
影响因子:
--
作者:
Parikh,ShamikJ;Yanovski,JackA
通讯作者:
Yanovski,JackA