Clinical significance of mobile health assessed sleep duration and variability in bipolar disorder.
Clinical significance of mobile health assessed sleep duration and variability in bipolar disorder.
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DOI：
10.1016/j.jpsychires.2016.07.008
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发表时间：
2016-10
影响因子：
4.8
通讯作者：
Depp, Colin A.
中科院分区：
文献类型：
--
作者：
Kaufmann, Christopher N.;Gershon, Anda;Eyler, Lisa T.;Depp, Colin A.
睡眠障碍是双相情感障碍的普遍性、持续性和损害性特征。然而，睡眠障碍的严重性和可变性对症状和功能的近期和累积影响仍不清楚。我们研究了自我报告的每日睡眠时间和变化与情绪症状，药物依从性，认知功能和并发的日常影响。41名诊断为双相情感障碍的门诊患者被要求提供11周内通过智能手机进行生态瞬时评估收集的睡眠持续时间和影响的每日报告。在基线时收集抑郁和躁狂症状、药物依从性和认知功能的测量结果，并每天收集情感评估结果。分析研究了睡眠持续时间或变异性是否与基线测量以及当天或第二天影响的变化相关。较大的睡眠持续时间变异性（而不是平均睡眠持续时间）与较大的抑郁和躁狂症状严重程度相关，基线时较低的药物依从性，以及较低和更多的积极情绪评分和较高的消极情绪评分。睡眠时间短于7-8小时与当天较低的积极情绪评分和当天较高的消极情绪评分相关，但这并没有延伸到第二天的情绪。更大的累积日间睡眠时间变异性，而不是平均睡眠时间，与更严重的情绪症状，更低的自我报告的药物依从性和更高水平的负面影响有关。短时间或长时间的睡眠对情绪有短暂的影响。日常睡眠的变化可能是重要的，纳入临床评估双相情感障碍的睡眠障碍。
Sleep disturbances are prevalent, persistent, and impairing features of bipolar disorder. However, the near-term and cumulative impact of the severity and variability of sleep disturbances on symptoms and functioning remains unclear. We examined self-reported daily sleep duration and variability in relation to mood symptoms, medication adherence, cognitive functioning, and concurrent daily affect. Forty-one outpatients diagnosed with bipolar disorder were asked to provide daily reports of sleep duration and affect collected via ecological momentary assessment with smartphones over eleven weeks. Measures of depressive and manic symptoms, medication adherence, and cognitive function were collected at baseline and concurrent assessment of affect were collected daily. Analyses examined whether sleep duration or variability were associated with baseline measures and changes in same-day or next-day affect. Greater sleep duration variability (but not average sleep duration) was associated with greater depressive and manic symptom severity, and lower medication adherence at baseline, and with lower and more variable ratings of positive affect and higher ratings of negative affect. Sleep durations shorter than 7-8 hours were associated with lower same-day ratings of positive and higher same-day ratings of negative affect, however this did not extend to next-day affect. Greater cumulative day-to-day sleep duration variability, but not average sleep duration, was related to more severe mood symptoms, lower self-reported medication adherence and higher levels of negative affect. Bouts of short- or long-duration sleep had transient impact on affect. Day-to-day sleep variability may be important to incorporate into clinical assessment of sleep disturbances in bipolar disorder.
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DOI：
10.1111/j.1468-2850.2009.01164.x
发表时间：
2009-06
期刊：
Clinical psychology : a publication of the Division of Clinical Psychology of the American Psychological Association
影响因子：
--
作者：
Harvey AG;Talbot LS;Gershon A
通讯作者：
Gershon A
影响因子：
6.6
作者：
Gruber, June;Miklowitz, David J.;Ketter, Terence A.
通讯作者：
Ketter, Terence A.
影响因子：
2.1
作者：
Albert, Mark V.;Deeny, Sean;Jayaraman, Arun
通讯作者：
Jayaraman, Arun
影响因子：
8.1
作者：
Goossens, P. J. J.;Kupka, R. W.;van Achterberg, T.
通讯作者：
van Achterberg, T.
影响因子：
12.8
作者：
Boland, Elaine M.;Alloy, Lauren B.
通讯作者：
Alloy, Lauren B.