Sleep disturbance and cognitive deficits in bipolar disorder: toward an integrated examination of disorder maintenance and functional impairment.

Sleep disturbance and cognitive deficits in bipolar disorder: toward an integrated examination of disorder maintenance and functional impairment.
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DOI:
10.1016/j.cpr.2012.10.001
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发表时间:
2013-02
影响因子:
12.8
通讯作者:
Alloy, Lauren B.
Alloy, Lauren B.
中科院分区:
心理学1区
文献类型:
--
作者:
Boland, Elaine M.;Alloy, Lauren B.

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双相情感障碍通常与一些不良结果相关,包括但不限于,尽管情绪症状缓解,但恢复到发病前职业和社会心理功能水平的能力明显受损。睡眠障碍是躁狂和抑郁发作后经常报道的残留症状,同样与躁狂发作有关。在情感发作期间以及发作间期,也有认知功能缺陷的报道,许多报道表明,这在这种持续性残疾中起着重要作用。尽管在情感发作和发作间期这两个功能领域存在缺陷,但没有对这些系统可能相互作用的程度进行评估,以维持如此高的功能残疾率。本综述的目的是研究双相情感障碍患者睡眠障碍和认知障碍之间的关系,以及这些领域的缺陷可能共同维持功能障碍的方式。
Bipolar disorder is frequently associated with a number of poor outcomes including, but not limited to, a significant impairment in the ability to return to premorbid levels of occupational and psychosocial functioning, often despite the remission of mood symptoms. Sleep disturbance is an oft-reported residual symptom of manic and depressive episodes that has likewise been associated with the onset of manic episodes. Also present during affective episodes as well as the inter-episode periods are reports of deficits in cognitive functioning, which many reports have shown to play an important role in this persistent disability. Despite the presence of deficits in these two domains of functioning during affective episodes as well as the inter-episode phase, there has been no evaluation of the degree to which these systems may interact to maintain such high rates of functional disability. The aim of this review is to examine evidence for the study of the relationship between sleep disturbance and cognitive impairments in bipolar disorder as well as the ways in which deficits in these domains may work together to maintain functional impairment.
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