Association of blood groups with ovarian reserve and outcome of in vitro fertilization treatment.

Association of blood groups with ovarian reserve and outcome of in vitro fertilization treatment.
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DOI:
10.5144/0256-4947.2016.31.3.1700
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发表时间:
2016-03
影响因子:
1.6
通讯作者:
Coskun S
Coskun S
中科院分区:
医学4区
文献类型:
--
作者:
Awartani K;Al Ghabshi R;Al Shankiti H;Al Dossari M;Coskun S

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ABO血型与不孕患者卵巢储备功能的关系一直是一个有争议的问题。本研究的目的是评估某些血型与接受不孕症治疗的患者的卵巢储备和治疗反应的相关性。回顾性病历审查。沙特阿拉伯利雅得费萨尔国王专科医院和研究中心辅助生殖技术部门的不孕症诊所。所有在2010年到三级保健中心不孕症诊所就诊并在2010年和2011年接受体外受精(IVF)治疗的40岁以下患者根据血型分组,并比较临床参数。使用第3天促黄体激素(LH)和促卵泡激素(FSH)水平以及窦卵泡计数(AFC)研究血型与卵巢储备之间的关系。在424例接受566个IVF周期的患者中,不同血型之间的年龄、LH、FSH和AFC相似(分别为P=.9、.1、.5)。在控制性卵巢刺激中,四组间绝经期促性腺激素(hMG)剂量或刺激持续时间无差异。获得的卵母细胞数量、受精率、卵裂率和移植的胚胎数量相似。各组之间的取消率或妊娠率没有差异。在我们的人群中,血型和IVF治疗期间的卵巢储备或反应之间没有显着相关性。抗苗勒管激素水平与卵巢储备测试最相关。AMH水平不可用。回顾性设计。
The association between ABO blood groups and ovarian reserve in infertile patients has been a point of controversy. The aim of this study was to assess the correlation of certain blood groups with ovarian reserve and response to treatment in patients undergoing infertility treatment. Retrospective medical record review. Infertility clinic in the assisted reproductive technology (ART) unit at King Faisal Specialist Hospital and Research Center, Riyadh Saudi Arabia. All patients under 40 years of age who attended the infertility clinic at a tertiary care centre in 2010 and underwent in vitro fertilization (IVF) treatment in 2010 and 2011 were divided into groups according to blood type, and clinical parameters were compared. The association between blood groups and ovarian reserve using day 3 luteinzing hormone (LH) and follicular stimulating hormone (FSH) levels, and antral follical count (AFC). In 424 patients who underwent 566 IVF cycles, age, LH, FSH and AFC were similar among the different blood groups (P=.9, .1, .5, respectively). With controlled ovarian stimulation, no difference was observed among the four groups in menopausal gonadotrophin (hMG) dose or the duration of stimulation. The number of oocytes retrieved, fertilization rate, cleavage rate, and number of embryos transferred were similar. There was no difference in the cancellation rate or pregnancy rate among the groups. There was no significant association between blood type and ovarian reserve or response during IVF treatment in our population. Anti-Mullerian hormone levels are best correlated with ovarian reserve testing. Unavailability of AMH levels. Retrospective design.
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发表时间: 2010-05
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发表时间: 1953-01-01
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