'Long COVID': persistent COVID-19 symptoms in survivors managed in Lagos State, Nigeria.
'Long COVID': persistent COVID-19 symptoms in survivors managed in Lagos State, Nigeria.
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DOI：
10.1186/s12879-020-05716-x
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发表时间：
2021-03-25
影响因子：
3.7
通讯作者：
Abayomi A
中科院分区：
文献类型：
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作者：
Osikomaiya B;Erinoso O;Wright KO;Odusola AO;Thomas B;Adeyemi O;Bowale A;Adejumo O;Falana A;Abdus-Salam I;Ogboye O;Osibogun A;Abayomi A
冠状病毒疾病曾经被认为是呼吸道感染，现在被认为是一种影响呼吸、心血管、胃肠道、神经、免疫和造血系统的多系统疾病。新出现的大量证据表明，在一些幸存者中，COVID-19症状以不同的模式持续存在。本研究旨在描述COVID-19幸存者的持续症状，并调查这些持续症状的可能风险因素。本研究采用回顾性研究设计。研究人群包括出院的COVID-19患者。在拉各斯州COVID-19门诊就诊的患者中评估了人口统计学信息、出院后天数、合并症和持续COVID-19样症状。使用STATA 15.0软件（StataCorp Texas）进行统计分析，显著性置于p值< 0.05。共有274例患者入组本研究。大多数患者年龄在35岁至≤49岁之间（38.3%），男性（66.1%）。超过三分之一（40.9%）的患者出院后有持续的COVID-19症状，19.7%的患者有三种以上持续的COVID样症状。最持久的COVID样症状是容易疲劳（12.8%），头痛（12.8%）和胸痛（9.8%）。与轻度严重程度相比，中度严重程度的症状性COVID-19疾病是出院后持续COVID样症状的预测因子（p < 0.05）。这项研究的结果表明，从COVID-19疾病中康复的患者可能仍然会出现COVID-19样症状，特别是疲劳和头痛。因此，出院后应进行仔细监测，以帮助减轻这些症状的影响，并改善COVID-19幸存者的生活质量。
Coronavirus disease once thought to be a respiratory infection is now recognised as a multi-system disease affecting the respiratory, cardiovascular, gastrointestinal, neurological, immune, and hematopoietic systems. An emerging body of evidence suggests the persistence of COVID-19 symptoms of varying patterns among some survivors. This study aimed to describe persistent symptoms in COVID-19 survivors and investigate possible risk factors for these persistent symptoms. The study used a retrospective study design. The study population comprised of discharged COVID-19 patients. Demographic information, days since discharge, comorbidities, and persistent COVID-19 like symptoms were assessed in patients attending the COVID-19 outpatient clinic in Lagos State. Statistical analysis was done using STATA 15.0 software (StataCorp Texas) with significance placed at p-value < 0.05. A total of 274 patients were enrolled in the study. A majority were within the age group > 35 to ≤49 years (38.3%), and male (66.1%). More than one-third (40.9%) had persistent COVID-19 symptoms after discharge, and 19.7% had more than three persistent COVID-like symptoms. The most persistent COVID-like symptoms experienced were easy fatigability (12.8%), headaches (12.8%), and chest pain (9.8%). Symptomatic COVID-19 disease with moderate severity compared to mild severity was a predictor of persistent COVID-like symptoms after discharge (p < 0.05). Findings from this study suggests that patients who recovered from COVID-19 disease may still experience COVID-19 like symptoms, particularly fatigue and headaches. Therefore, careful monitoring should be in place after discharge to help mitigate the effects of these symptoms and improve the quality of life of COVID-19 survivors.
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影响因子：
5.8
作者：
Boelaert K;Visser WE;Taylor PN;Moran C;Léger J;Persani L
通讯作者：
Persani L
DOI：
10.34172/ijtmgh.2020.09
发表时间：
2020-01-01
影响因子：
--
作者：
Olufadewa, Isaac Iyinoluwa;Adesina, Miracle Ayomikun;Abudu, Funmilayo
通讯作者：
Abudu, Funmilayo
影响因子：
15.1
作者：
Mazza, Mario Gennaro;De Lorenzo, Rebecca;Benedetti, Francesco
通讯作者：
Benedetti, Francesco
影响因子：
1.2
作者：
Bowale, Abimbola;Abayomi, Akin;Osibogun, Akin
通讯作者：
Osibogun, Akin
DOI：
10.1007/s00259-020-05084-3
发表时间：
2021-05
影响因子：
9.1
作者：
Sollini M;Ciccarelli M;Cecconi M;Aghemo A;Morelli P;Gelardi F;Chiti A
通讯作者：
Chiti A