Higher Body Mass Index Is Associated with Subjective Olfactory Dysfunction.
Higher Body Mass Index Is Associated with Subjective Olfactory Dysfunction.
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DOI：
10.1155/2015/675635
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发表时间：
2015
影响因子：
2.8
通讯作者：
Wise SK
中科院分区：
文献类型：
--
作者：
Patel ZM;DelGaudio JM;Wise SK
背景病态肥胖患者表现出嗅觉灵敏度的改变。目前还没有研究直接评估嗅觉功能障碍患者的体重指数（BMI）。我们的目的是比较一组有主观嗅觉功能障碍的患者与没有主观嗅觉投诉的患者的BMI。方法.回顾性配对病例对照研究。60例患者谁提出了一个三级保健耳鼻喉科中心主观嗅觉功能障碍超过一年。排除了肿瘤和梗阻性病因。对人口统计学、BMI和吸烟状况进行了审查。选择60名年龄、性别和种族匹配的对照患者进行比较。使用卡方检验。结果嗅觉功能障碍组60名患者中有48名（80%）属于超重或肥胖类别，而对照组60名患者中有36名（60%）。对于该分层BMI，嗅觉功能障碍组和对照组之间存在统计学显著差异（p = 0.0168）。这项研究表明，高BMI与嗅觉功能障碍有关。前瞻性临床研究应进一步研究这一点，以确定增加BMI是否可能是嗅觉丧失的危险因素，并阐明嗅觉丧失在肥胖患者的饮食和喂养习惯中可能发挥的作用。
Background. Morbidly obese patients demonstrate altered olfactory acuity. There has been no study directly assessing Body Mass Index (BMI) in patients with olfactory dysfunction. Our purpose was to compare BMI in a group of patients with subjective olfactory dysfunction to those without subjective olfactory complaints. Methods. Retrospective matched case-control study. Sixty patients who presented to a tertiary care otolaryngology center with subjective smell dysfunction over one year were identified. Neoplastic and obstructive etiologies were excluded. Demographics, BMI, and smoking status were reviewed. Sixty age, gender, and race matched control patients were selected for comparison. Chi-square testing was used. Results. 48 out of 60 patients (80%) in the olfactory dysfunction group fell into the overweight or obese categories, compared to 36 out of 60 patients (60%) in the control group. There was a statistically significant difference between the olfactory dysfunction and control groups for this stratified BMI (p = 0.0168). Conclusion. This study suggests high BMI is associated with olfactory dysfunction. Prospective clinical research should examine this further to determine if increasing BMI may be a risk factor in olfactory loss and to elucidate what role olfactory loss may play in diet and feeding habits of obese patients.
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影响因子：
2.6
作者：
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通讯作者：
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