Prevalence of pollen-induced allergic rhinitis with high pollen exposure in grasslands of northern China.
Prevalence of pollen-induced allergic rhinitis with high pollen exposure in grasslands of northern China.
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作者：
Wang XY;Ma TT;Wang XY;Zhuang Y;Wang XD;Ning HY;Shi HY;Yu RL;Yan D;Huang HD;Bai YF;Shan GL;Zhang B;Song QK;Zhang YF;Zhang TJ;Jia DZ;Liu XL;Kang ZX;Yan WJ;Yang BT;Bao XZ;Sun SH;Zhang FF;Yu WH;Bai CL;Wei T;Yang T;Ma TQ;Wu XB;Liu JG;Du H;Zhang L;Yan Y;Wang DY
本研究的目的是调查中国北方草原地区流行病学和医生诊断的花粉诱导AR（PiAR）的患病率，并研究花粉暴露强度和时间对PiAR患病率的影响。进行了多阶段、整群和按比例分层随机抽样，并进行了现场访问者管理的调查研究，同时进行了皮肤点刺试验（SPT）和每日花粉计数测量。共有6043例受试者完成了研究，流行病学AR和PiAR的比例分别为32.4%和18.5%。男性患病率高于女性（19.6% vs 17.4%，P = 0.024），但两个主要居住和民族（汉族和蒙古族）之间没有观察到差异。城市人群的PiAR患病率高于农村人群（23.1%vs14.0%，P <0.001）。大多数PiAR患者对两种或两种以上的花粉（79.4%）致敏，其中蒿属、藜属和草属是最常见的花粉类型，也是SPT发现的前三大致敏花粉过敏原。6个地区流行性变应性鼻炎（18.6%~ 52.9%）和副变应性鼻炎（10.5%~ 31.4%）的患病率存在显著的地区差异。PiAR症状与花粉数、温度和降水量呈正相关（P <0.05），但与风速和气压呈负相关（P <0.05）。由于季节性花粉暴露量高，受当地环境和气候条件的影响，研究地区的花粉诱导AR（PiAR）患病率极高。
The aim of this study was to investigate the prevalence of epidemiologic and physician‐diagnosed pollen‐induced AR (PiAR) in the grasslands of northern China and to study the impact of the intensity and time of pollen exposure on PiAR prevalence. A multistage, clustered and proportionately stratified random sampling with a field interviewer‐administered survey study was performed together with skin prick tests (SPT) and measurements of the daily pollen count. A total of 6043 subjects completed the study, with a proportion of 32.4% epidemiologic AR and 18.5% PiAR. The prevalence was higher in males than females (19.6% vs 17.4%, P = .024), but no difference between the two major residential and ethnic groups (Han and Mongolian) was observed. Subjects from urban areas showed higher prevalence of PiAR than rural areas (23.1% vs 14.0%, P < .001). Most PiAR patients were sensitized to two or more pollens (79.4%) with artemisia, chenopodium, and humulus scandens being the most common pollen types, which were similarly found as the top three sensitizing pollen allergens by SPT. There were significant regional differences in the prevalence of epidemiologic AR (from 18.6% to 52.9%) and PiAR (from 10.5% to 31.4%) among the six areas investigated. PiAR symptoms were positively associated with pollen counts, temperature, and precipitation (P < .05), but negatively with wind speed and pressure P < .05). Pollen‐induced AR (PiAR) prevalence in the investigated region is extremely high due to high seasonal pollen exposure, which was influenced by local environmental and climate conditions.
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影响因子：
12.4
作者：
Hellings, P. W.;Fokkens, W. J.;Bousquet, J.
通讯作者：
Bousquet, J.
影响因子：
5
作者：
Matyasovszky, Istvan;Makra, Laszlo;Suemeghy, Zoltan
通讯作者：
Suemeghy, Zoltan
影响因子：
2.8
作者：
Sakashita, Masafumi;Hirota, Tomomitsu;Fujieda, Shigeharu
通讯作者：
Fujieda, Shigeharu
影响因子：
1.1
作者：
Makra, Laszlo;Tombacz, Szintia;Hirsch, Tamas
通讯作者：
Hirsch, Tamas
影响因子：
5.9
作者：
Fuhrman, Claire;Sarter, Helene;Caillaud, Denis
通讯作者：
Caillaud, Denis