The human amygdala is necessary for developing and expressing normal interpersonal trust.
The human amygdala is necessary for developing and expressing normal interpersonal trust.
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DOI：
10.1016/j.neuropsychologia.2010.09.023
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发表时间：
2011-03
期刊：
影响因子：
2.6
通讯作者：
Tranel D
中科院分区：
文献类型：
--
作者：
Koscik TR;Tranel D
众所周知，人类的杏仁核参与处理社会、情感和奖励相关的信息。先前的报告表明，杏仁核参与从面部提取可信度信息。有趣的是，功能性神经成像研究使用可能需要发展和/或表达人际信任的经济任务，如信任游戏（TG），并没有常规地确定杏仁核的参与。本研究旨在探索杏仁核在发展和表达人际信任中的作用，通过多轮，多人经济交换，一种版本的TG，在一个大样本的局灶性脑损伤参与者中。杏仁核单侧受损的参与者在TG中表现出更多的仁慈行为，特别是，他们倾向于增加对背叛的信任。另一方面，神经正常的成年人倾向于以实物回报信任，即他们对背叛的反应是减少人际信任，对他人的增加的反应是增加信任。相比之下，不包括杏仁核、腹内侧前额叶或岛叶皮质的脑损伤的参与者，倾向于对他人表达的信任或背叛表现出矛盾。我们的数据表明，杏仁核是发展和表达正常人际信任所必需的。面对他人的背叛，他们表现得更加仁慈，这可能与在这一群体中观察到的异常社会行为有关。此外，增加的仁慈可能会增加被他人利用的可能性或机会。
The human amygdala is known to be involved in processing social, emotional, and reward-related information. Previous reports have indicated that the amygdala is involved in extracting trustworthiness information from faces. Interestingly, functional neuroimaging research using economic tasks that presumably require developing and/or expressing interpersonal trust, such as the Trust Game (TG), have not routinely identified involvement of the amygdala. The present study sought to explore the role of the amygdala in developing and expressing interpersonal trust, via a multi-round, multiplayer economic exchange, a version of the TG, in a large sample of participants with focal brain damage. Participants with unilateral damage to the amygdala displayed increased benevolent behavior in the TG, and specifically, they tended to increase trust in response to betrayals. On the other hand, neurologically-normal adults tended to repay trust in kind, i.e., they decreased interpersonal trust in response to betrayals or increased trust in response to increases from others. Comparison participants, with brain damage that does not include the amygdala, ventromedial prefrontal or insular cortices, tended to behave ambivalently to the expressed trust or betrayal of others. Our data suggest that the amygdala is necessary for developing and expressing normal interpersonal trust. This increased tendency to behave benevolently in response to defections from others may be related to the abnormal social behavior observed in this group. Moreover, increased benevolence may increase the likelihood or opportunity to be taken advantage of by others.
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影响因子：
64.8
作者：
Kosfeld, M;Heinrichs, M;Fehr, E
通讯作者：
Fehr, E
DOI：
10.1111/j.1749-6632.2010.05445.x
发表时间：
2010-01-01
期刊：
YEAR IN COGNITIVE NEUROSCIENCE 2010
影响因子：
--
作者：
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通讯作者：
Adolphs, Ralph
影响因子：
56.9
作者：
King-Casas, B;Tomlin, D;Montague, PR
通讯作者：
Montague, PR
影响因子：
3.2
作者：
Engell, Andrew D.;Haxby, James V.;Todorov, Alexander
通讯作者：
Todorov, Alexander
影响因子：
56.9
作者：
Hsu, M;Bhatt, M;Camerer, CF
通讯作者：
Camerer, CF