Photonic crystals: emerging biosensors and their promise for point-of-care applications.
Photonic crystals: emerging biosensors and their promise for point-of-care applications.
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DOI：
10.1039/c6cs00206d
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发表时间：
2017-01-23
影响因子：
46.2
通讯作者：
Demirci U
中科院分区：
文献类型：
--
作者：
Inan H;Poyraz M;Inci F;Lifson MA;Baday M;Cunningham BT;Demirci U
生物传感器被广泛用于诊断世界范围内临床环境中的各种疾病和病症。在诸如初级诊所或床边的护理点（POC）处的生物传感器的实施面临障碍，因为它们可能需要训练有素的人员，具有长的测定时间、大尺寸和高仪器成本。因此，需要在POC处开发廉价、可靠、用户友好且紧凑的生物感测系统。与光子晶体（PC）结构结合的生物传感器有望解决新POC诊断开发所面临的许多上述挑战。目前，基于PC的生物传感器已被用于检测各种生物靶标，如细胞，病原体，蛋白质，抗体和核酸，具有高效率和选择性。在这篇评论中，我们提供了一个广泛的概述，通过解释他们的结构，制造技术和传感原理的PC。此外，我们还讨论了最近的应用基于PC的生物传感器结合新兴技术，包括远程医疗，柔性和可穿戴传感，智能材料和超材料。最后，我们讨论了与现有的生物传感器相关的当前挑战，并提供了一个基于PC的生物传感器和他们的承诺在POC的前景。
Biosensors are extensively employed for diagnosing a broad array of diseases and disorders in clinical settings worldwide. The implementation of biosensors at the point-of-care (POC), such as at primary clinics or the bedside, faces impediments because they may require highly trained personnel, have long assay times, large sizes, and high instrumental cost. Thus, there exists a need to develop inexpensive, reliable, user-friendly, and compact biosensing systems at the POC. Biosensors incorporated with photonic crystal (PC) structures hold promise to address many of the aforementioned challenges facing the development of new POC diagnostics. Currently, PC-based biosensors have been employed for detecting a variety of biotargets, such as cells, pathogens, proteins, antibodies, and nucleic acids, with high efficiency and selectivity. In this review, we provide a broad overview of PCs by explaining their structures, fabrication techniques, and sensing principles. Furthermore, we discuss recent applications of PC-based biosensors incorporated with emerging technologies, including telemedicine, flexible and wearable sensing, smart materials and metamaterials. Finally, we discuss current challenges associated with existing biosensors, and provide an outlook for PC-based biosensors and their promise at the POC.
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影响因子：
8.4
作者：
Cai Z;Luck LA;Punihaole D;Madura JD;Asher SA
通讯作者：
Asher SA
DOI：
10.1111/j.1751-553x.2008.01050.x
发表时间：
2008-04-01
影响因子：
3
作者：
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DOI：
10.1186/2049-3258-72-28
发表时间：
2014
期刊：
Archives of public health = Archives belges de sante publique
影响因子：
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作者：
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通讯作者：
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影响因子：
4.6
作者：
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