Long COVID occurrence in COVID-19 survivors.
Long COVID occurrence in COVID-19 survivors.
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DOI：
10.1038/s41598-022-10051-z
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发表时间：
2022-04-11
影响因子：
4.6
通讯作者：
Tanaka J
中科院分区：
文献类型：
--
作者：
Sugiyama A;Miwata K;Kitahara Y;Okimoto M;Abe K;E B;Ouoba S;Akita T;Tanimine N;Ohdan H;Kubo T;Nagasawa A;Nakanishi T;Takafuta T;Tanaka J
这项横断面研究旨在调查 COVID-19 的急性后后果。我们于 2020 年 8 月至 2021 年 3 月期间在日本广岛县的两家指定的 COVID-19 医院对后遗症、心理困扰 (K6)、工作表现障碍 (WFun) 以及与 COVID-19 相关的耻辱和歧视经历进行了自填式问卷调查。后遗症的发生率是根据年龄和 COVID-19 严重程度计算的。使用逻辑回归分析确定与后遗症或心理困扰独立相关的因素。在 127 名从 COVID-19 中康复的患者中，52.0% 的患者在 COVID-19 发病后平均 29 天 [IQR 23-128] 内出现持续症状。在轻度 COVID-19 患者中，49.5% 出现后遗症。最常见的症状是嗅觉障碍（15.0%）、味觉障碍（14.2%）和咳嗽（14.2%）。多变量分析显示，年龄是后遗症的独立危险因素（调整后的比值比[AOR]， ≥ 60岁与 < 40岁为3.63，p = 0.0165）。 30.7% 的人（男性 17.9%，女性 45.0%）表示可能存在心理困扰。女性性别和后遗症的存在是心理困扰的独立危险因素。在所有参与者中，29.1% 的人可能存在工作表现受损的情况。 43.3% 的参与者表示曾遭受过耻辱和歧视。这项研究揭示了长新冠病毒对当地社区健康的重大影响。需要进行大规模、长期的队列研究。
This cross-sectional study aimed to investigate the post-acute consequences of COVID-19. We conducted a self-administered questionnaire survey on sequelae, psychological distress (K6), impairments in work performance (WFun), and COVID-19–related experiences of stigma and discrimination in two designated COVID-19 hospitals in Hiroshima Prefecture, Japan, between August 2020 and March 2021. The prevalence of sequelae was calculated by age and COVID-19 severity. Factors independently associated with sequelae or psychological distress were identified using logistic regression analysis. Among 127 patients who had recovered from COVID-19, 52.0% had persistent symptoms at a median of 29 days [IQR 23–128] after COVID-19 onset. Among patients with mild COVID-19, 49.5% had sequelae. The most frequent symptoms were olfactory disorders (15.0%), taste disorders (14.2%), and cough (14.2%). Multivariate analysis showed that age was an independent risk factor for sequelae (adjusted odds ratios [AOR] for ≥ 60 years vs. < 40 years 3.63, p = 0.0165). Possible psychological distress was noted in 30.7% (17.9% of males and 45.0% of females). Female sex and the presence of sequelae were independent risk factors for psychological distress. Of all participants, 29.1% had possible impairments in work performance. Experiences of stigma and discrimination were reported by 43.3% of participants. This study revealed the significant impacts of Long COVID on health in local communities. A large-scale, long-term cohort study is desired.
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DOI：
10.1016/j.jinf.2021.01.004
发表时间：
2021-03
期刊：
The Journal of infection
影响因子：
--
作者：
Moreno-Pérez O;Merino E;Leon-Ramirez JM;Andres M;Ramos JM;Arenas-Jiménez J;Asensio S;Sanchez R;Ruiz-Torregrosa P;Galan I;Scholz A;Amo A;González-delaAleja P;Boix V;Gil J;COVID19-ALC research group
通讯作者：
COVID19-ALC research group
影响因子：
4.6
作者：
D'Cruz, Rebecca F.;Waller, Michael D.;Jolley, Caroline J.
通讯作者：
Jolley, Caroline J.
影响因子：
82.9
作者：
Blomberg B;Mohn KG;Brokstad KA;Zhou F;Linchausen DW;Hansen BA;Lartey S;Onyango TB;Kuwelker K;Sævik M;Bartsch H;Tøndel C;Kittang BR;Bergen COVID-19 Research Group;Cox RJ;Langeland N
通讯作者：
Langeland N
影响因子：
4
作者：
Lukiw, Walter J.;Pogue, Aileen;Hill, James M.
通讯作者：
Hill, James M.
影响因子：
--
作者：
Kessler, RC;Barker, PR;Zaslavsky, AM
通讯作者：
Zaslavsky, AM