Evaluation of diastolic function by three-dimensional volume tracking of the mitral annulus with cardiovascular magnetic resonance: comparison with tissue Doppler imaging.
Evaluation of diastolic function by three-dimensional volume tracking of the mitral annulus with cardiovascular magnetic resonance: comparison with tissue Doppler imaging.
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DOI：
10.1186/s12968-014-0071-3
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发表时间：
2014-09-20
期刊：
影响因子：
--
通讯作者：
Axel L
中科院分区：
文献类型：
--
作者：
Wu V;Chyou JY;Chung S;Bhagavatula S;Axel L
二尖瓣环（MA）动力学的测量是评价左心室（LV）舒张功能的重要组成部分; MA速度通常使用组织多普勒成像（TDI）测量。本研究旨在检查半自动心血管磁共振（CMR）技术的临床潜力，用于量化整体LV舒张功能，使用常规电影CMR图像的MA的3D体积跟踪。124例射血分数正常的连续患者在2个月内接受了临床指征经胸超声心动图（TTE）和CMR。在长轴电影CMR图像中使用半自动房室结（AVJ）跟踪进行MA随时间推移的插值3D重建，在心动周期内产生MA扫描体积。使用以下参数评价基于CMR的舒张功能：早期舒张期峰值容积扫描率（PSRE）和心房收缩期峰值容积扫描率（PSRA）、PSRE/PSRA比值、扫描容积减速时间（DTSV）和50%舒张期扫描容积恢复时间（DSVRT 50）;将这些参数与TTE舒张测量值进行比较。与基于TTE的舒张功能正常的患者（n = 62）相比，基于TTE的舒张功能障碍患者（n = 62）显示出显著不同的标准化MA扫描容积曲线，包括较低的PSRE（5.25 ± 1.38 s-1与7.72 ± 1.7 s-1），更高的PSRA（6.56 ± 1.99 s-1与4.67 ± 1.38 s-1），PSRE/PSRA比率较低（0.9 ± 0.44 vs. 1.82 ± 0.69），DTSV更长（144 ± 55 ms vs. 96 ± 37 ms），DSVRT 50更长（25.0 ± 11.0% vs. 15.6 ± 4.0%）（所有p < 0.05）。在校正左心室肥厚、高血压和冠状动脉疾病后，CMR舒张参数是基于TTE的舒张功能障碍的独立预测因子。CMR PSRE/PSRA与TDI测量的舒张早期与晚期瓣环流速比（e′/a′）之间具有良好的相关性（r = 0.756 ~ 0.828，p < 0.001）。在常规采集的CMR图像中通过半自动AVJ跟踪生成的3D MA扫描体积产生舒张参数，当与基于TTE的变量相关时，这些参数可有效识别舒张功能障碍患者。
Measurement of mitral annulus (MA) dynamics is an important component of the evaluation of left ventricular (LV) diastolic function; MA velocities are commonly measured using tissue Doppler imaging (TDI). This study aimed to examine the clinical potential of a semi-automated cardiovascular magnetic resonance (CMR) technique for quantifying global LV diastolic function, using 3D volume tracking of the MA with conventional cine-CMR images. 124 consecutive patients with normal ejection fraction underwent both clinically indicated transthoracic echocardiography (TTE) and CMR within 2 months. Interpolated 3D reconstruction of the MA over time was performed with semi-automated atrioventricular junction (AVJ) tracking in long-axis cine-CMR images, producing an MA sweep volume over the cardiac cycle. CMR-based diastolic function was evaluated, using the following parameters: peak volume sweep rates in early diastole (PSRE) and atrial systole (PSRA), PSRE/PSRA ratio, deceleration time of sweep volume (DTSV), and 50% diastolic sweep volume recovery time (DSVRT50); these were compared with TTE diastolic measurements. Patients with TTE-based diastolic dysfunction (n = 62) showed significantly different normalized MA sweep volume profiles compared to those with TTE-based normal diastolic function (n = 62), including a lower PSRE (5.25 ± 1.38 s−1 vs. 7.72 ± 1.7 s−1), a higher PSRA (6.56 ± 1.99 s−1 vs. 4.67 ± 1.38 s−1), a lower PSRE/PSRA ratio (0.9 ± 0.44 vs. 1.82 ± 0.69), a longer DTSV (144 ± 55 ms vs. 96 ± 37 ms), and a longer DSVRT50 (25.0 ± 11.0% vs. 15.6 ± 4.0%) (all p < 0.05). CMR diastolic parameters were independent predictors of TTE-based diastolic dysfunction after adjusting for left ventricular hypertrophy, hypertension, and coronary artery disease. Good correlations were observed between CMR PSRE/PSRA and early-to-late diastolic annular velocity ratios (e′/a′) measured by TDI (r = 0.756 to 0.828, p < 0.001). 3D MA sweep volumes generated by semi-automated AVJ tracking in routinely acquired CMR images yielded diastolic parameters that were effective in identifying patients with diastolic dysfunction when correlated with TTE-based variables.
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DOI：
10.1186/1532-429x-12-46
发表时间：
2010-07-31
期刊：
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
影响因子：
--
作者：
Mendoza DD;Codella NC;Wang Y;Prince MR;Sethi S;Manoushagian SJ;Kawaji K;Min JK;LaBounty TM;Devereux RB;Weinsaft JW
通讯作者：
Weinsaft JW
影响因子：
2.8
作者：
DOUGHERTY, AH;NACCARELLI, GV;GOLDSTEIN, RA
通讯作者：
GOLDSTEIN, RA
影响因子：
37.8
作者：
LEVINE, RA;HANDSCHUMACHER, MD;WEYMAN, AE
通讯作者：
WEYMAN, AE
影响因子：
24
作者：
Hogg, K;Swedberg, K;McMurray, J
通讯作者：
McMurray, J
影响因子：
1.6
作者：
Fujii, Toshiharu;Yoshioka, Koichiro;Nakano, Masataka;Nakazawa, Gaku;Amino, Mari;Masuda, Naoki;Shinozaki, Norihiko;Kanda, Shigetaka;Ogata, Nobuhiko;Deguchi, Yoshiaki;Yoshimachi, Fuminobu;Ikari, Yuji
通讯作者：
Ikari, Yuji