Impaired decision making in adolescent suicide attempters.
Impaired decision making in adolescent suicide attempters.
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DOI：
10.1016/j.jaac.2012.01.002
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发表时间：
2012-04
影响因子：
13.3
通讯作者：
Brent DA
中科院分区：
文献类型：
--
作者：
Bridge JA;McBee-Strayer SM;Cannon EA;Sheftall AH;Reynolds B;Campo JV;Pajer KA;Barbe RP;Brent DA
决策缺陷与成年人的自杀行为有关。然而，目前尚不清楚决策障碍是否在青少年自杀行为的发病机制中起作用。本研究的目的是检查青少年自杀企图者和从未自杀的比较对象的决策过程。使用爱荷华赌博任务，作者检查了40名13-18岁的青少年自杀未遂者和40名人口统计学上匹配的从未自杀的精神病学比较对象的决策。总的来说，自杀企图者在爱荷华赌博任务中的表现明显比比较对象差。在控制了情感障碍、当前精神药物使用、冲动和敌意的条件logistic回归分析中，两组之间总体任务表现的差异持续存在（调整优势比=0.96,95%置信区间= 0.90-0.99,p< 0.05）。双向重复测量的方差分析揭示了显著的组块交互作用，表明尝试者在任务中未能学习，在任务的第一个和最后一个块中选择的不利卡片的比例大致相同。相比之下，随着任务的进行，比较对象从不利的牌组中选择的牌按比例减少。在尝试者组中，总体任务表现与指数尝试的任何特征或与冲动性、敌意和情绪不稳定的人格维度无关。与成年人的研究结果相似，青少年的决策能力受损与自杀行为有关。需要纵向研究来阐明决策过程与自杀行为之间的时间关系，并帮助制定早期识别和预防干预的潜在目标，以减少青少年自杀和自杀行为。
Decision-making deficits have been linked to suicidal behavior in adults. However, it remains unclear whether impaired decision-making plays a role in the etiopathogenesis of youth suicidal behavior. The purpose of this study was to examine decision-making processes in adolescent suicide attempters and never-suicidal comparison subjects. Using the Iowa Gambling Task, the authors examined decision-making in 40 adolescent suicide attempters, ages 13–18, and 40 never-suicidal, demographically-matched psychiatric comparison subjects. Overall, suicide attempters performed significantly worse on the Iowa Gambling Task than comparison subjects. This difference in overall task performance between the groups persisted in an exact conditional logistic regression analysis that controlled for affective disorder, current psychotropic medication use, impulsivity, and hostility (adjusted odds ratio=0.96, 95% confidence interval=0.90–0.99, p<.05). A two-way repeated-measures analysis of variance revealed a significant group-by-block interaction, demonstrating that attempters failed to learn during the task, picking approximately the same proportion of disadvantageous cards in the first and final blocks of the task. In contrast, comparison subjects picked proportionately fewer cards from the disadvantageous decks as the task progressed. Within the attempter group, overall task performance did not correlate with any characteristic of the index attempt or with the personality dimensions of impulsivity, hostility, and emotional lability. Similar to findings in adults, impaired decision-making is associated with suicidal behavior in adolescents. Longitudinal studies are needed to elucidate the temporal relationship between decision-making processes and suicidal behavior and help frame potential targets for early identification and preventive interventions to reduce youth suicide and suicidal behavior.
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DOI：
10.1097/00004583-199505000-00013
发表时间：
1995-05-01
影响因子：
13.3
作者：
FERGUSSON, DM;LYNSKEY, MT
通讯作者：
LYNSKEY, MT
影响因子：
3.8
作者：
Diamond, Pamela M.;Magaletta, Philip R.
通讯作者：
Magaletta, Philip R.
DOI：
10.1002/ajmg.c.30042
发表时间：
2005-02-15
影响因子：
3.1
作者：
Brent, DA;Mann, JJ
通讯作者：
Mann, JJ
影响因子：
7.8
作者：
Courtet, P.;Guillaume, S.;Jollanta, F.
通讯作者：
Jollanta, F.
DOI：
10.1097/00004583-199301000-00010
发表时间：
1993-01-01
影响因子：
13.3
作者：
BRENT, DA;JOHNSON, B;CONSTANTINE, D
通讯作者：
CONSTANTINE, D