Syntrophy in anaerobic global carbon cycles.
Syntrophy in anaerobic global carbon cycles.
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DOI：
10.1016/j.copbio.2009.10.001
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发表时间：
2009-12
影响因子：
7.7
通讯作者：
Gunsalus, Robert P.
中科院分区：
文献类型：
--
作者：
McInerney, Michael J.;Sieber, Jessica R.;Gunsalus, Robert P.
在有机物厌氧转化为甲烷的过程中，互养是一个必不可少的中间步骤，其中代谢上不同的微生物通过需要将交换的代谢物保持在非常低的浓度而紧密联系在一起。对互养的需要在生物学上受到限制，并且可能是难以培养微生物的主要原因，因为这些方法破坏了聚生体。人工互养聚生体的重建使得未培养的互养代谢菌和产甲烷菌能够最佳地生长和生物化学研究。互养乙酸盐、丙酸盐和长链脂肪酸代谢的途径大多已被了解，但苯甲酸盐分解和环己烷羧酸盐形成的关键步骤尚不清楚。互养代谢需要反向电子转移、密切的身体接触和互养伙伴的代谢同步。基因组分析表明，存在多种机制的反向电子转移。令人惊讶的是，鞭毛的功能涉及确保密切的物理接近和互养伙伴的同步。
Syntrophy is an essential intermediary step in the anaerobic conversion of organic matter to methane where metabolically distinct microorganisms are tightly linked by the need to maintain the exchanged metabolites at very low concentrations. The need for syntrophy is thermodynamically constrained, and is probably a prime reason why it is difficult to culture microbes as these approaches disrupt consortia. Reconstruction of artificial syntrophic consortia has allowed uncultured syntrophic metabolizers and methanogens to be optimally grown and studied biochemically. The pathways for syntrophic acetate, propionate and longer chain fatty acid metabolism are mostly understood, but key steps involved in benzoate breakdown and cyclohexane carboxylate formation are unclear. Syntrophic metabolism requires reverse electron transfer, close physical contact, and metabolic synchronization of the syntrophic partners. Genomic analyses reveal that multiple mechanisms exist for reverse electron transfer. Surprisingly, the flagellum functions were implicated in ensuring close physical proximity and synchronization of the syntrophic partners.
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影响因子：
4.4
作者：
Chauhan, A;Ogram, A
通讯作者：
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影响因子：
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作者：
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DOI：
10.1099/ijs.0.64398-0
发表时间：
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影响因子：
2.8
作者：
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通讯作者：
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影响因子：
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作者：
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通讯作者：
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