Body-worn motion sensors detect balance and gait deficits in people with multiple sclerosis who have normal walking speed.
Body-worn motion sensors detect balance and gait deficits in people with multiple sclerosis who have normal walking speed.
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DOI：
10.1016/j.gaitpost.2011.11.026
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发表时间：
2012-04
期刊：
影响因子：
2.4
通讯作者：
Bourdette, D.
中科院分区：
文献类型：
--
作者：
Spain, R. I.;George, R. J. St.;Salarian, A.;Mancini, M.;Wagner, J. M.;Horak, F. B.;Bourdette, D.
虽然平衡和步态限制是多发性硬化症（MS）的标志，但临床上实际使用的标准秒表计时措施对最小影响患者不敏感。这妨碍了对行动不便的早期发现和干预。这项研究试图确定穿戴式传感器是否能检测出行走速度正常的多发性硬化症患者和健康对照者在平衡和步态方面的差异。31名MS和28名年龄和性别匹配的对照组受试者在安静的姿势和步态（计时起身和行走测试，TUG）中使用身体穿戴式传感器进行测试。结果与秒表计时的测量结果进行了比较。拖船和计时25英尺步行测试的秒表持续时间在组间无显著差异。然而，在闭眼安静站立时，MS患者的摇摆加速度幅度明显大于对照组（p = 0.02）。在步态过程中，MS患者在侧倾（中侧向屈曲，p = 0.017）和偏航（轴向旋转，p = 0.026）平面上的躯干角运动范围更大。MS患者180°转弯持续时间也更长（p = 0.031）。因此，当传统的定时测试无法检测到MS和健康对照之间的活动能力差异时，穿戴式运动传感器检测到了MS和健康对照之间的活动能力差异。这种便携式技术提供了以前在临床中无法获得的客观和定量的活动能力数据，并且可能被证明是MS早期活动能力变化的有用结果测量。
While balance and gait limitations are hallmarks of multiple sclerosis (MS), standard stopwatch-timed measures practical for use in the clinic are insensitive in minimally affected patients. This prevents early detection and intervention for mobility problems. The study sought to determine if body-worn sensors could detect differences in balance and gait between people with MS with normal walking speeds and healthy controls. Thirty-one MS and twenty-eight age- and sex-matched control subjects were tested using body-worn sensors both during quiet stance and gait (Timed Up and Go test, TUG). Results were compared to stopwatch-timed measures. Stopwatch durations of the TUG and Timed 25 Foot Walk tests were not significantly different between groups. However, during quiet stance with eyes closed, people with MS had significantly greater sway acceleration amplitude than controls (p = 0.02). During gait, people with MS had greater trunk angular range of motion in roll (medio-lateral flexion, p = 0.017) and yaw (axial rotation, p = 0.026) planes. Turning duration through 180° was also longer in MS (p = 0.031). Thus, body-worn motion sensors detected mobility differences between MS and healthy controls when traditional timed tests could not. This portable technology provides objective and quantitative mobility data previously not obtainable in the clinic, and may prove a useful outcome measure for early mobility changes in MS.
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DOI：
10.1109/titb.2011.2107916
发表时间：
2011-05-01
影响因子：
--
作者：
Palmerini, Luca;Rocchi, Laura;Chiari, Lorenzo
通讯作者：
Chiari, Lorenzo
影响因子：
9.2
作者：
Kuo, AD
通讯作者：
Kuo, AD
DOI：
10.1191/135245800678827860
发表时间：
2000-08-01
期刊：
MULTIPLE SCLEROSIS
影响因子：
--
作者：
Kaufman, M;Moyer, D;Norton, J
通讯作者：
Norton, J
DOI：
10.1177/135245850100700311
发表时间：
2001-06-01
期刊：
MULTIPLE SCLEROSIS
影响因子：
--
作者：
Bowen, J;Gibbons, L;Kraft, GH
通讯作者：
Kraft, GH
影响因子：
2.2
作者：
Cattaneo, Davide;Regola, Alberto;Meotti, Matteo
通讯作者：
Meotti, Matteo