The mediating role of depression in the relationship between anxiety sensitivity and alcohol dependence.
The mediating role of depression in the relationship between anxiety sensitivity and alcohol dependence.
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抑郁在焦虑敏感性与酒精依赖关系中的中介作用.
DOI：
10.1016/j.addbeh.2014.04.002
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发表时间：
2014
影响因子：
4.4
通讯作者：
Lejuez,CW
中科院分区：
文献类型：
--
作者：
Lechner,WilliamV;Shadur,JuliaM;Banducci,AnneN;Grant,DeMondM;Morse,Melanie;Lejuez,CW
背景许多研究报告称，焦虑敏感性（AS）与饮酒或其他与酒精相关的变量呈正相关。最近的中介者和调节者模型在阐明这种关系中的机制方面表现出了希望。迄今为止的文献表明，AS 和酒精之间的关系可能是由有问题的应对动机介导的。然而，尽管有大量证据表明 AS 与随后的抑郁症以及抑郁症与随后的饮酒问题独立相关，但很少有研究考虑 AS 与饮酒关系中抑郁症的影响。因此，当前的研究将抑郁症评估为这种关系的潜在中介因素。 方法 参与者为连续入住药物滥用治疗机构的 418 名参与者。利用自举中介分析来估计 AS 通过抑郁对酒精依赖的间接影响。结果结果揭示了间接影响，表明焦虑敏感性对酒精依赖的影响是由抑郁症状介导的。更具体地说，AS 总分和 AS 躯体感觉对酒精依赖的影响是由抑郁症状介导的。最后，双重中介模型表明，抑郁症和问题应对方式独特地介导了 AS 和酒精依赖之间的关系。结论虽然是初步的，但当前的研究提供了支持以下假设的证据：抑郁是检查 AS 和酒精依赖之间的关系时需要考虑的重要因素。
BackgroundMany studies have reported that Anxiety Sensitivity (AS) is positively associated with alcohol use or other alcohol-related variables. More recent mediator and moderator models have shown promise in elucidating mechanisms within this relationship; the literature to date suggests that the relationship between AS and alcohol is likely mediated by problematic coping motives. However, few studies have considered the effects of depression within the AS–alcohol use relationship, despite a strong body of evidence linking AS to subsequent depression and depression to subsequent alcohol use problems, independently. Therefore, the current study assessed depression as a potential mediator of this relationship.MethodParticipants were 418 sequential admissions to a substance abuse treatment facility. A mediation analysis using bootstrapping was utilized in order to estimate indirect effects of AS on alcohol dependence through depression.ResultsResults reveal an indirect effect suggesting that the effects of anxiety sensitivity on alcohol dependence are mediated by symptoms of depression. More specifically, the effects of AS total score and AS somatic sensations on alcohol dependence were mediated by symptoms of depression. Lastly, a dual mediator model demonstrated that both depression and problematic coping uniquely mediate the relationship between AS and alcohol dependence.ConclusionsWhile preliminary in nature, the current study provides evidence supporting the hypothesis that depression is an important factor to consider when examining the relationship between AS and alcohol dependence.
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影响因子：
2.8
作者：
Cox, BJ;Enns, MW;Taylor, S
通讯作者：
Taylor, S
与抑郁症状相关的认知失调的恐惧：焦虑敏感性的原始测量和替代测量之间的比较。
DOI：
10.1016/s0005-7916(99)00026-9
发表时间：
1999
影响因子：
1.8
作者：
B. Cox;S. Taylor;M. Enns
通讯作者：
M. Enns
焦虑敏感度的维度
影响因子：
10.3
作者：
R. Zinbarg;J. Mohlman;N. N. Hong
通讯作者：
N. N. Hong
DOI：
10.1111/j.1530-0277.1998.tb04297.x
发表时间：
1998-05-01
影响因子：
3.2
作者：
Conrod, PJ;Pihl, RO;Vassileva, J
通讯作者：
Vassileva, J
焦虑敏感性、焦虑和抑郁之间关联的纵向、遗传信息研究
影响因子：
2.6
作者：
H. Zavos;F. Rijsdijk;T. Eley
通讯作者：
T. Eley